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Frozen in liquid nitrogen.
Human iPSC-Derived Neural Progenitor Cells (Cat. No. CIPC-NWC001) have the ability to differentiate into dopamine neurons (Cat. No. CIPC-DWC001) .
Haloperidol-Induced Modulation of Neuronal Firing
This data set demonstrates the dose-dependent effects of Haloperidol on neuronal firing. Raster plots and associated firing parameters (for Weighted Mean Firing Rate, Number of Bursts, Burst Duration and Burst Frequency, n = 3; for Number of Network Bursts, n = 2) are presented for varying Haloperidol concentrations. At 0.1 μM, the firing activity is enhanced, while at 1 μM, the activity diminishes. At 10 μM, the firing is nearly abolished. These results are consistent with findings from Yokoi et al. (2019), where Haloperidol is known to inhibit D2 receptors at low doses and 5-HT2 receptors at high doses (Tyler et al., 2017). This confirms that the relevant receptors in our Human iPSC-Derived Dopamine Neurons are functioning normally, underscoring their utility in drug screening and neurotoxicity studies.
Explore our catalog of therapeutic antibody solutions to find the right products for you! We are dedicated to delivering solutions designed to help you drive innovation and push the boundaries of what therapeutic antibodies can be.
We offer a wide range of cell and gene therapy solutions starting from discovery to the clinic. Explore our wide range of proteins, antibodies, kits, and other assays to accelerate the development of your cell and gene therapy.
Organoid Toolbox is a collection of organoid solutions including ready-to-use organoids, organoid differentiation kits, and a variety of services to accelerate the progress of your drug development project.
ACROBiosystems developed a series of GMP grade cytokines under the GMP grade quality management system. Those products are all suitable for T/NK cell generation, activation, and proliferation in cell therapy research.
50+ targets designed for CAR detection, including PE/FITC/biotin labeled proteins. The key reagents for CD19 and BCMA were FDA DMF filed which can support your IND, NDA and BLA process.
Full length multi-pass TPs with stabilized structure and high bioactivity for immunization, antibody screening, cell based assay and CAR detection, including hot CD20, Claudin 18.2， CD133, GPRC5D，CCR8, CCR5, etc.
GMP grade cytokines, reagents for cell activation, gene edition, DNA/RNA removal, etc. Particularly focus on product design, quality control and solution-based support to link each phase of your cell and gene therapy journey.
A series of immune checkpoints including classic co-inhibitory and co-stimulatory receptors. The comprehensive catalog contains 100+ targets with various species and tags, and the high-quality proteins are in good batch-to-batch consistency.
To meet the needs of ADCs development, ACROBiosystems can provide: A variety of high-quality target proteins; MMPs/Cathepsin/uPA for cleavable linker; Anti-payload antibodies & anti-idiotypic antibodies for immunogenicity and PK analysis; SPR/BLI analytical and ADA development service.
Comprehensive collection of Fc receptor proteins, including their common variants, which can help expedite your antibody development.
Comprehensive cytokine targets including interleukins, growth factors, chemokines, TNFs, etc. are expressed by HEK293 to ensure their natural structure. Their high purity is verified by SDS-PAGE/HPLC/SEC-MALS and high bioactivity is verified by ELISA/SPR/BLI.
Aneuro provides innovative solutions for neuroscience research. Recombinant proteins, neural factors, pre-formed fibrils, electrophysiological electrodes, as well as Organoid Toolbox all in Aneuro aiming to advance neuroscience research, develop therapeutic interventions, and improve diagnostic methods for neurological diseases.
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