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Aneuro | Neural Factors Neural factors are a class of protein molecules with neurotrophic activity that can promote the survival and regeneration of nerve cells. At present, more and more neural factors have been found to play a neuroprotective role in stroke, brain injury and other diseases. Once peripheral nerves are injured, protecting neurons from apoptosis is a prerequisite for nerve regeneration. Exogenous neural factors can promote survival of different types of neurons. Recent studies have shown that the combined effect of multiple factors in repairing peripheral nerve injury is better than that of a single factor, because nerve injury can cause changes in the levels of multiple peripheral neurotrophic factors and their receptors, and participate in nerve repair together. Therefore, the combined action of nerve factors is more inclined to the actual state in the body and can improve the protective effect of neurons.
As the brand of ACROBiosystems that focused on neuroscience, Aneuro has developed a series of recombinant neural factors to support the culture and differentiation of nerve cells.
Molecule | Cat. No. | Product Description |
---|---|---|
Artemin | ARN-H5118 | Human Artemin Protein, Tag Free |
BDNF | BDF-H5219 | Human BDNF Protein, Native |
Beta-NGF | BEF-H5214 | Human Beta-NGF Protein, Tag Free |
CNTF | CNF-H5114 | Human CNTF Protein, Tag Free |
CNTF R alpha | CNR-H5225 | Human CNTF R alpha Protein, His Tag |
GDNF | GDF-H5219 | Human GDNF / ATF Protein, His Tag |
GDF-M5245 | Mouse GDNF / ATF Protein, His Tag | |
GMF-beta | GMA-H5145 | Human GMF-beta Protein, His Tag (MALS verified) |
MANF | MAF-H52H3 | Human MANF Protein, His Tag (MALS verified) |
Midkine | MIE-H5117 | Human Midkine / Mdk Protein, Tag Free |
MIE-M5246 | Mouse Midkine / Mdk Protein, His Tag | |
MIE-M82Q8 | Biotinylated Mouse Midkine / Mdk Protein, His,Avitag™ | |
NT-3 | NT3-H5115 | Human NT-3 / Neurotrophin-3 Protein, Tag Free |
NT-4 | NT4-H5114 | Human NT-4 / Neurotrophin-4 Protein, Tag Free, low endotoxin (MALS verified) |
NGFR | NGR-H5254 | Human NGFR / TNFRSF16 Protein, Fc Tag |
Pleiotrophin | PLN-H5244 | Human Pleiotrophin / PTN Protein, His Tag |
TrkA | TRA-H5253 | Human TrkA / NTRK1 (192-402) Protein, Mouse IgG2a Fc Tag |
TRA-H5259 | Human TrkA / NTRK1 (33-417) Protein, Mouse IgG2a Fc Tag | |
TrkB | NT2-H5228 | Human TrkB / NTRK2 Protein, His Tag |
NT2-H5254 | Human TrkB / NTRK2 Protein, Fc Tag | |
TrkC | TRC-H5256 | Human TrkC / NTRK3 Protein, Fc Tag |
[1] Ascano M, Bodmer D, Kuruvilla R. Endocytic trafficking of neurotrophins in neural development. Trends Cell Biol, 2012, 22:266 - 273.
[2] Shakhbazau A, Martinez JA, Xu QG, et al. Evidence for a systemic regulation of neurotrophin synthesis in response to peripheral nerve injury. J Neurochem, 2012, 122: 501-511.
[3] Liu K P, Ma W, Li C Y, et al. Neurotrophic factors combined with stem cells in the treatment of sciatic nerveinjury in rats: a metaanalysis. Biosci Rep, 2022, 42(1): BSR20211399
[4] Jafari M, Delaviz H, Torabi S, et al. The effect of muscle graft with nerve growth factor and laminin on sciatic nerve repair in rats. Basic ClinNeurosci. 2019, 10(4):333-344
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