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Your Position: Home > DR3

DR3

Brief Information

Name:Tumor necrosis factor receptor superfamily member 25
Target Synonym:Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,Protein WSL,DDR3,Death Receptor Beta,TNFRSF12,TRAMP,DR3,WSL-1,PH Domain-Containing Family G Member 5,PLEKHG5,WSL-LR,WSL1,APO3,WSL,TR3,TNF Receptor Superfamily Member 25,Death Domain Receptor 3 Soluble Form,GEF720,Guanine Nucleotide Exchange Factor 720,Apoptosis Inducing Receptor,Tumor Necrosis Factor Receptor Superfamily, Member 25,Ple
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

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Cat. No. Species Product Description Structure Purity Feature
DR3-H82E3 Human Biotinylated Human DR3 / TNFRSF25 Protein, His,Avitag™ (MALS verified)
DR3-H82E3-structure
DR3-H82E3-sds
DR3-H82F3 Human Biotinylated Human DR3 / TNFRSF25 Protein, Fc,Avitag™ (MALS verified)
DR3-H82F3-structure
DR3-H82F3-sds
DR3-H5253 Human Human DR3 Protein, Fc Tag (MALS verified)
DR3-H5253-structure
DR3-H5253-sds
TN5-H52H3 Human Human DR3 / TNFRSF25 Protein, His Tag
TN5-H52H3-structure
TN5-H52H3-sds
TN5-C5257 Cynomolgus Cynomolgus DR3 / TNFRSF25 Protein, Fc Tag
TN5-C5257-structure
TN5-C5257-sds
ACRO Quality

Part of Bioactivity data

DR3-H5253-SPR
DR3 SPR

Human DR3 Protein, Fc Tag (Cat. No. DR3-H5253) captured on Protein A Chip can bind Human TL1A, His Tag (Cat. No. TLA-H5243) with an affinity constant of 7.58 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
TN5-H52H3-SPR
DR3 SPR

Human DR3 Protein, His Tag (Cat. No. TN5-H52H3) immobilized on CM5 Chip can bind Biotinylated Human TL1A Protein, His,Avitag (Cat. No. TLA-H52Q1) with an affinity constant of 97.9 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
PTX-35 PTX-35 Phase 1 Clinical Heat Biologics Solid tumours Details
PTX-35 PTX-35 Phase 1 Clinical Heat Biologics Solid tumours Details

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