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Her2

Brief Information

Name:Receptor protein-tyrosine kinase erbB-2
Target Synonym:EC 2.7.10.1,HER-2/Neu,Herstatin,HER-2,TKR1,Receptor, ErbB-2,V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog,V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2,Neuroblastoma/Glioblastoma Derived Oncogene Homolog,C-Erb B2/Neu Protein,CD340 Antigen,EC:2.7.10.1,EC 2.7.10,MLN 19,CD340,Tyrosine kinase-type cell surface receptor HER2,Receptor tyrosine-protein kinase erbB-2,ERBB2,MLN19,Proto-oncogene Neu,Erb-B2 Receptor Tyrosine Kinase 2,V-E
Number of Launched Drugs:35
Number of Drugs in Clinical Trials:200
Lastest Research Phase:Approved

Licensing

Project Name Modality Therapeutic Area Indications Stage Right Available
Anti-Her2 II / Anti-Her2 IV Bi-specific antibody ADC Bioconjugates Oncology/Cancer Solid tumor Preclinical Global
Her2xCD3 BsAb Bispecific antibody Oncology/Cancer HER2-positive Cancer Phase I Global

Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
HE2-M82F3 Mouse Biotinylated Mouse Her2 / ErbB2 Protein, Fc,Avitag™ (MALS verified)
HE2-M82F3-structure
HE2-M82F3-sds
CHEK-ATP150 Human HEK293/Human ErbB2 Stable Cell Line
HE2-M82E3 Mouse Biotinylated Mouse Her2 / ErbB2 Protein, His,Avitag™ (MALS verified)
HE2-M82E3-structure
HE2-M82E3-sds
HE2-M5253 Mouse Mouse Her2 / ErbB2 Protein, Fc Tag (MALS verified)
HE2-M5253-structure
HE2-M5253-sds
HE2-C5253 Cynomolgus Cynomolgus Her2 / ErbB2 Protein, Fc Tag
HE2-C5253-structure
HE2-C5253-sds
HE2-C82F3 Cynomolgus Biotinylated Cynomolgus Her2 / ErbB2 Protein, Fc,Avitag™
HE2-C82F3-structure
HE2-C82F3-sds
CAA-B004 Rabbit HER2 IHC 5D5 Kit
MBS-C006 Human ActiveMax® Human Her2 μBeads, premium grade (for cells)
HGS-S254 Rabbit Recombinant Monoclonal Anti-HER2 Antibody, Rabbit (5D5)
HE2-HA2H9 Human APC-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HP2H8 Human PE-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HA2H3 Human Alexa Fluor™ 488-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HA2H4 Human Alexa Fluor™ 555-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HA2H5 Human Alexa Fluor™ 647-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HA2H7 Human APC-Labeled Human Her2 / ErbB2 Protein, His Tag (Site-specific conjugation)
HE2-HA2H7-structure
HE2-R52H8 Rabbit Rabbit Her2 / ErbB2 Protein, His Tag
HE2-R52H8-structure
HE2-R52H8-sds
HE2-HF256 Human FITC-Labeled Human Her2 / ErbB2 Protein, Fc Tag
HE2-HF256-structure
HE2-HF256-sds
HE2-HP2E3 Human PE-Labeled Human Her2 / ErbB2 Protein, His Tag (Site-specific conjugation)
HE2-HP2E3-structure
HE2-H52H9 Human Human Her2 / ErbB2 (23-510) Protein, His Tag (MALS verified)
HE2-H52H9-structure
HE2-H52H9-sds
HE2-H52H3 Human Human Her2 / ErbB2 (S310Y) Protein, His Tag (MALS verified)
HE2-H52H3-structure
HE2-H52H3-sds
HE2-H52H2 Human Human Her2 / ErbB2 (S310F) Protein, His Tag
HE2-H52H2-structure
HE2-H52H2-sds
MBS-K006 Human Human HER2-coupled Magnetic Beads
HE2-H52H4 Human Human Her2 / ErbB2 (498-648) Protein, His Tag
HE2-H52H4-structure
HE2-H52H4-sds
HE2-HF224 Human FITC-Labeled Human Her2 / ErbB2 Protein, His Tag
HE2-HF224-structure
HE2-HF224-sds
HE2-H5255 Human Human Her2 / ErbB2 Protein, Mouse IgG2a Fc Tag (MALS verified)
HE2-H5255-structure
HE2-H5255-sds
HE2-C82E3 Cynomolgus Biotinylated Cynomolgus Her2 / ErbB2 Protein, His,Avitag™ (MALS verified)
HE2-C82E3-structure
HE2-C82E3-sds
HE2-H5212 Human Human Her2 / ErbB2 Protein, Tag Free
HE2-H5212-structure
HE2-H5212-sds
HE2-C52Hb Cynomolgus Cynomolgus Her2 / ErbB2 Protein, His Tag (MALS verified)
HE2-C52Hb-structure
HE2-C52Hb-sds
EHH-V1 Human ELISA Assay Kit for Anti-HER-2 h-mAb in Human Serum
EHM-V1 Mouse ELISA Assay Kit for Anti-HER-2 h-mAb in Mouse Serum
EHC-V1 Monkey ELISA Assay Kit for Anti-HER-2 h-mAb in Monkey Serum
HE2-H82E2 Human Biotinylated Human Her2 / ErbB2 Protein, His,Avitag™, premium grade
HE2-H82E2-structure
HE2-H82E2-sds
HE2-H822R Human Biotinylated Human Her2 / ErbB2 Protein, His Tag, ultra sensitivity (primary amine labeling, long spacer)
HE2-H822R-structure
HE2-H822R-sds
HE2-H5287 Human Human Her2 / ErbB2 Protein, Twin-Strep Tag
HE2-H5287-structure
HE2-H5287-sds
ER2-M5220 Mouse Mouse Her2 / ErbB2 Protein, His Tag
ER2-M5220-structure
ER2-M5220-sds
HE2-H5253 Human Human Her2 / ErbB2 Protein, Fc Tag, premium grade
HE2-H5253-structure
HE2-H5253-sds
HE2-H5225 Human Human Her2 / ErbB2 Protein, His Tag (MALS verified)
HE2-H5225-structure
HE2-H5225-sds
ACRO Quality

Part of Bioactivity data

HE2-HA2H9-Cell-based assay
 Her2 CAR_T

5e5 of anti-Her2 CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer) of APC-Labeled Human Her2, His Tag (Cat. No. HE2-HA2H9) and negative control protein respectively (Fig. C and B), and non-transfected 293 cells were used as a control (Fig. A). APC signal was used to evaluate the binding activity (QC tested).

HE2-H82E2-SPR
 Her2 SPR

Biotinylated Human Her2, His,Avitag, premium grade (Cat. No. HE2-H82E2) immobilized on SA Chip can bind Trastuzumab with an affinity constant of 7.82 pM as determined in a SPR assay (Biacore 8K) (Routinely tested).

HE2-H5225-SPR
 Her2 SPR

Herceptin (Trastuzumab) captured on CM5 chip via anti-human IgG Fc antibodies surface, can bind Human Her2, His Tag (Cat. No. HE2-H5225) with an affinity constant of 1.07 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Customer Reviews

Synonym Name

ERBB2,CD340,HER-2/neu,HER2,MLN19,NEU,NGL,TKR1

Background

Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2,HER-2 /neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation .

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Trastuzumab biosimilar (AryoGen Pharmed) Approved Aryogen Biopharma AryoTrust Stomach Neoplasms; Breast Neoplasms Details
Trastuzumab/Hyaluronidase Approved Genentech Inc Herceptin Hylecta United States Breast Neoplasms Genentech Inc 2019-02-28 Breast Neoplasms Details
Dacomitinib PF-00299804-03; PF-00299804-3; PF-00299804; PF-299804; PF-299; PF-804 Approved Pfizer Inc Vizimpro United States Carcinoma, Non-Small-Cell Lung Pfizer Inc 2018-09-27 Colorectal Neoplasms; Adenocarcinoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Penile Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Mouth Neoplasms; Lung Neoplasms; Solid tumours; Brain Neoplasms; Liver Diseases; Carcinoma, Large Cell; Glioblastoma; Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Head and Neck Neoplasms Details
Trastuzumab biosimilar (Zhejiang Hisun Pharmaceutical) HS-022 Approved Zhejiang Hisun Pharmaceutical Co Ltd 安瑞泽 Mainland China Stomach Neoplasms; Breast Neoplasms Hisun Biopharmaceutical Co Ltd 2023-02-28 Stomach Neoplasms; Breast Neoplasms Details
Pertuzumab rhuMab-2C4; RO-4368451; R-1273; RG-1273; RO-4368451-F01; rhuMAb2C4; Ro 436-8451/F01; RO4368451 Approved Genentech Inc, F. Hoffmann-La Roche Ltd 帕捷特, Perjeta, Omnitarg United States Breast Neoplasms Genentech Inc 2012-06-08 Neuroendocrine Tumors; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Multiple Endocrine Neoplasia; Fallopian Tube Neoplasms; Carcinoma, Neuroendocrine; Peritoneal Neoplasms; Prostatic Neoplasms; Neuroblastoma; Breast Neoplasms; Adrenal Gland Neoplasms; Ovarian Neoplasms; Neoplasms; Pancreatic neuroendocrine tumors (pNET); Pancreatic Neoplasms; Colonic Neoplasms; Carcinoid Tumor; Stomach Neoplasms; Esophageal Neoplasms; Rectal Neoplasms; Solid tumours Details
Trastuzumab biosimilar (Synthon) ABP-980 Approved Synthon Bv Kanjinti EU Breast Neoplasms; Stomach Neoplasms Amgen Europe Bv 2018-05-16 Urinary Bladder Neoplasms; Melanoma; Adenocarcinoma; Uterine Cervical Neoplasms; Thyroid Neoplasms; Uterine Neoplasms; Esophageal adenocarcinoma; Endometrial Neoplasms; Lung Neoplasms; Lymphoma; Glioma; Colorectal Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cholangiocarcinoma; Prostatic Neoplasms; Breast Neoplasms; Liver Neoplasms; Multiple Myeloma; Colonic Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Ovarian Epithelial; Skin Neoplasms; Carcinoma, Renal Cell; Rectal Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Solid tumours Details
Afatinib Dimaleate BIBW-2992-MA2; BIBW-2992 Approved C.H. Boehringer Sohn Ag & Co. Kg Gilotrif, Giotrif, Tovok, 吉泰瑞, Tomtovok United States Carcinoma, Non-Small-Cell Lung C.H. Boehringer Sohn Ag & Co. Kg 2013-07-12 Esophageal Squamous Cell Carcinoma; Urethral Neoplasms; Brain Neoplasms; Prostatic Neoplasms; Ureteral Neoplasms; Urologic Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Squamous Cell; Breast Neoplasms; Gallbladder Neoplasms; Uterine Neoplasms; Lymphoma; Glioma; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Neoplasm Metastasis; Rhabdomyosarcoma; Multiple Myeloma; Liver Diseases; Chordoma; Urinary Bladder Neoplasms; Neoplasms, Squamous Cell; Glioblastoma; Neuroectodermal Tumors; Neoplasms; Renal Insufficiency; Stomach Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Hematologic Neoplasms; Solid tumours; Head and Neck Neoplasms Details
Trastuzumab biosimilar (Biocon/Mylan) Bmab-200; Myl-1401O; HerMyl-1401O Approved Biocon Ltd, Mylan Nv CANMAb, Ogivri, Zedora, Hertraz India Breast Neoplasms; Esophageal Neoplasms; Stomach Neoplasms null 2013-01-01 Esophageal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Esophageal adenocarcinoma; Uterine Cervical Neoplasms; Adenocarcinoma Details
Margetuximab MGAH-22 Approved Macrogenics Inc Margenza United States Breast Neoplasms Macrogenics Inc 2020-12-16 Ovarian Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Digestive System Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Neoplasm Metastasis; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Pyrotinib Maleate HTI-1001; SHR-1258; BLTN Approved Jiangsu Hengrui Medicine Co Ltd 艾瑞妮 Mainland China Breast Neoplasms Jiangsu Hengrui Medicine Co Ltd 2018-08-12 Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Adenocarcinoma of Lung; Neoplasms; Breast Neoplasms; Bile Duct Neoplasms; Lung Neoplasms; Metastatic breast cancer; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Tucatinib ARRY-380; ONT-380; MK-7119 Approved Array Biopharma Tukysa United States Breast Neoplasms Seagen Inc 2020-04-17 Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Breast Neoplasms; Meningeal Neoplasms; Colorectal Neoplasms; Hepatic Insufficiency; Metastatic breast cancer; Neoplasm Metastasis Details
Trastuzumab/Pertuzumab RO-7198574; RG-6264 Approved F. Hoffmann-La Roche Ltd Phesgo, 赫捷康 United States Breast Neoplasms Genentech Inc 2020-06-29 Breast Neoplasms; Colorectal Neoplasms; Metastatic breast cancer Details
Trastuzumab biosimilar (CTTQ Pharma) TQ-B211 Approved Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 赛妥 Mainland China Breast Neoplasms; Stomach Neoplasms Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group 2023-07-25 Stomach Neoplasms; Breast Neoplasms; Metastatic breast cancer Details
Trastuzumab R-597; RO45-2317; Anti-HER2/neu-MAb; huMAb4D5-8; RG-597; MKC-454 Approved Genentech Inc Herceptin, 赫赛汀 United States Breast Neoplasms Genentech Inc 1998-09-25 Prostatic Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Adenocarcinoma; Vulvar Diseases; Lung Neoplasms; Metastatic breast cancer; Endometrial Neoplasms; Urologic Neoplasms; Carcinoma, Mucoepidermoid; Carcinoma, Acinar Cell; Sarcoma; Urethral Neoplasms; Neoplastic Cells, Circulating; Breast Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Transitional Cell; Salivary Gland Neoplasms; Colonic Neoplasms; Neoplasms; Meningeal Carcinomatosis; Esophageal Neoplasms; Stomach Neoplasms; Solid tumours; Ependymoma; Head and Neck Neoplasms Details
Trastuzumab biosimilar (Biocad) BCD-022 Approved Biocad HERtiCAD Russian Federation Breast Neoplasms Biocad 2016-01-01 Breast Neoplasms Details
Disitamab Vedotin RC-48-ADC; RC48-ADC; RC-48 Approved RemeGen Co Ltd Aidixi, 爱地希 Mainland China Stomach Neoplasms RemeGen Co Ltd 2021-06-08 Urinary Bladder Neoplasms; Neoplasm Metastasis; Uterine Cervical Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Metastatic breast cancer; Endometrial Neoplasms; Genital Neoplasms, Female; Breast Diseases; Bile Duct Neoplasms; Breast Neoplasms; Ovarian Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Genital Diseases, Female; Esophageal Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Liver Neoplasms; Biliary Tract Neoplasms; Solid tumours Details
Trastuzumab biosimilar (Intas Pharmaceuticals) Approved Intas Biopharmaceuticals Breast Neoplasms Details
Trastuzumab biosimilar (Reliance Life Sciences) R-TPR-016 Approved Reliance Life Sciences TrastuRel India Breast Neoplasms Reliance Life Sciences 2015-01-01 Breast Neoplasms Details
Trastuzumab biosimilar (EirGenix/Sandoz) EG-12014; EGI 014A1; EGI-014 Approved Sandoz, Eirgenix Inc EU Breast Neoplasms; Stomach Neoplasms Sandoz Gmbh 2023-11-15 Stomach Neoplasms; Breast Neoplasms Details
Trastuzumab emtansine biosimilar (Zydus Cadila) ZRC-3256 Approved Zydus Cadila Ujvira India Breast Neoplasms Zydus Cadila 2021-05-24 Breast Neoplasms Details
Sunvozertinib DZD-9008 Approved Dizal (Jiangsu) Pharmaceutical Co Ltd 舒沃哲 Mainland China Carcinoma, Non-Small-Cell Lung Dizal (Jiangsu) Pharmaceutical Co Ltd 2023-08-22 Lymphoma, B-Cell; Hepatic Insufficiency; Lymphoma, Non-Hodgkin; Carcinoma, Non-Small-Cell Lung Details
Osimertinib Mesylate AZD-9291; RDL94R2A16; AZD-9291 Mesylate; AZD9291 Approved Astrazeneca Pharmaceutical Co Ltd 泰瑞沙, Tagrisso United States Carcinoma, Non-Small-Cell Lung Astrazeneca Pharmaceutical Co Ltd 2015-11-13 Brain metastases; Prostatic Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Colorectal Neoplasms; Meningeal Neoplasms; Endometrial Neoplasms; Uterine Neoplasms; Lung Neoplasms; Carcinoma, Squamous Cell; Multiple Myeloma; Esophageal adenocarcinoma; Thyroid Neoplasms; Glioma; Lymphoma; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Melanoma; Adenocarcinoma; Adenocarcinoma of Lung; Head and Neck Neoplasms; Ovarian Neoplasms; Liver Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Rectal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Solid tumours; Neoplasms; Carcinoma, Ovarian Epithelial; Glioblastoma; Carcinoma, Transitional Cell; Skin Neoplasms; Colonic Neoplasms; Pancreatic Neoplasms; Urinary Bladder Neoplasms Details
Trastuzumab biosimilar (Anke Biotech) Approved Anhui Anke Biotechnology (Group) Co Ltd Mainland China Breast Neoplasms Anhui Anke Biotechnology (Group) Co Ltd 2023-10-27 Breast Neoplasms Details
Inetetamab CMAB-302 Approved Cipterbin, 赛普汀 Mainland China Breast Neoplasms Sunshine Guojian Pharmaceutical (Shanghai) Co Ltd 2020-06-17 Breast Neoplasms Details
Trastuzumab biosimilar (Celltrion) CT-P6; CT-P06 Approved Celltrion Inc Herzuma South Korea Stomach Neoplasms; Breast Neoplasms null 2014-01-01 Stomach Neoplasms; Breast Neoplasms Details
Lapatinib Ditosylate Hydrate GW-572016; GW-572016F; GW-2016 Approved Glaxosmithkline Plc, Novartis Pharma Ag Tykerb, Tyverb, 泰立沙, Tykerb/Tyverb United States Breast Neoplasms Novartis Pharma Ag 2007-03-13 Gallbladder Neoplasms; Gliosarcoma; Colorectal Neoplasms; Astrocytoma; Bile Duct Neoplasms; Carcinoma, Acinar Cell; Carcinoma, Mucoepidermoid; Endometrial Neoplasms; Neoplasms, Gonadal Tissue; Lung Neoplasms; Carcinoma, Squamous Cell; Glioma; Laryngeal Neoplasms; Prostatic Neoplasms; Brain metastases; Lymphoma; Uterine Cervical Neoplasms; Adenocarcinoma; Melanoma; Tongue Neoplasms; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Neuroma, Acoustic; Carcinoma, Hepatocellular; Neoplasm Metastasis; Glioblastoma; Ovarian Neoplasms; Ependymoma; Head and Neck Neoplasms; Liver Neoplasms; Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Carcinoma; Abdominal Neoplasms; Salivary Gland Neoplasms; Medulloblastoma; Carcinoma, Verrucous; Neoplasms; Neurofibromatosis 2; Carcinoma, Ovarian Epithelial; Pancreatic Neoplasms; Central Nervous System Neoplasms; Urinary Bladder Neoplasms; Oligodendroglioma; Carcinoma, Adenoid Cystic; Breast Neoplasms; B Details
Trastuzumab biosimilar (Pfizer) PF-5280014; PF-05280014 Approved Pfizer Inc Trazimera, trastuzumab-qyyp EU Breast Neoplasms; Stomach Neoplasms Pfizer Europe Ma Eeig 2018-07-26 Urinary Bladder Neoplasms; Melanoma; Uterine Cervical Neoplasms; Esophageal adenocarcinoma; Lung Neoplasms; Lymphoma; Thyroid Neoplasms; Uterine Neoplasms; Endometrial Neoplasms; Glioma; Colorectal Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Multiple Myeloma; Head and Neck Neoplasms; Colonic Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Rectal Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Solid tumours; Liver Neoplasms; Ovarian Neoplasms Details
Trastuzumab biosimilar (Dr. Reddy's Laboratories) Approved Dr.Reddy's Laboratories Ltd Hervycta India Breast Neoplasms Dr.Reddy's Laboratories Ltd 2018-07-26 Breast Neoplasms Details
Ado-trastuzumab emtansine RG-3502; R-3502; T-DM1; PRO-132365; RO-5304020 Approved Genentech Inc Kadcyla, 赫赛莱 United States Breast Neoplasms Genentech Inc 2013-02-22 Hematologic Neoplasms; Solid tumours; Stomach Neoplasms; Pancreatic Neoplasms; Salivary Gland Neoplasms; Urinary Bladder Neoplasms; Multiple Myeloma; Breast Neoplasms; Cholangiocarcinoma; Urologic Neoplasms; Lymphoma; Lung Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
Trastuzumab biosimilar (Shanghai Henlius Biotech) HLX-02 Approved Shanghai Henlius Biotech Inc Zercepac, 汉曲优 EU Breast Neoplasms; Stomach Neoplasms Accord Healthcare Slu 2020-07-27 Stomach Neoplasms; Neoplasms; Breast Neoplasms Details
Trastuzumab biosimilar (Zydus) Approved Zydus Cadila Vivitra India Breast Neoplasms Zydus Cadila 2016-01-01 Breast Neoplasms Details
Trastuzumab biosimilar (AXXO) Approved Axxo Breast Neoplasms Details
Trastuzumab biosimilar (Samsung Bioepis) AMT-901; SB-3 Approved Samsung Bioepis Co Ltd Samfenet, Ontruzant EU Stomach Neoplasms; Breast Neoplasms Samsung Bioepis Nl Bv 2017-11-15 Stomach Neoplasms; Breast Neoplasms Details
Neratinib Maleate CAN-030; PB-272; HKI-272; PF-0528767; WAY-179272 Approved Pfizer Pharmaceuticals Ltd (China) Nerlynx, 贺俪安 United States Breast Neoplasms Puma Biotechnology Inc 2017-07-17 Solid tumours; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Hepatic Insufficiency; Colorectal Neoplasms; Lung Neoplasms; Brain metastases; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung Details
Fam-trastuzumab deruxtecan DS-8201a; DS-8201; VRN-101099 Approved Daiichi Sankyo Co Ltd Enhertu, 优赫得, 優赫得 United States Breast Neoplasms Daiichi Sankyo Co Ltd 2019-12-20 Breast Neoplasms; Carcinoma, Endometrioid; Uterine Cervical Neoplasms; Gastrointestinal Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Brain metastases; Metastatic breast cancer; Meningeal Neoplasms; Colorectal Neoplasms; Brain Neoplasms; Osteosarcoma; Solid tumours; Urinary Bladder Neoplasms; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Glioblastoma; Triple Negative Breast Neoplasms; Neoplasms, Glandular and Epithelial; Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Ovarian Neoplasms; Biliary Tract Neoplasms Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
ELVN-002 ELVN-002 Phase 1 Clinical Enliven Therapeutics Inc Breast Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung Details
Trastuzumab biosimilar (BioIntegrator) BI-Mab-03 Phase 1 Clinical Biointegrator Llc Breast Neoplasms Details
Hemay-022 Hemay-022 Phase 3 Clinical Tianjin Hemay Pharmaceutical Co Ltd, Xiajiang Hemei Pharmaceutical Co Ltd Breast Neoplasms; Foodborne Diseases Details
AU-101 AU-101 Phase 2 Clinical Aurora Biopharma Glioblastoma; Osteosarcoma; Breast Neoplasms Details
Pertuzumab biosimilar (biocad) BCD-178 Phase 1 Clinical Biocad Breast Neoplasms Details
CIDeCAR Phase 1 Clinical Bellicum Pharmaceuticals Inc, National Cancer Institute Osteosarcoma Details
Recombinant anti-HER2 human monoclonal antibody-DM1 (Hisun Pharm/Mabworks Biotech) HS-630; HS630 Phase 1 Clinical Zhejiang Hisun Pharmaceutical Co Ltd, Beijing Mabworks Biotech Co Ltd Breast Neoplasms Details
99mTc- ADAPT6 99mTc- ADAPT6; ADAPT6; SNA-018 Phase 1 Clinical Uppsala University, Kth Royal Institute Of Technology Breast Neoplasms Details
Puvitinib Phase 1 Clinical Suzhou Teligene Ltd Solid tumours Details
GB-251 GB-251; NBT-828; GB221-NBT828 ADC-1 Phase 1 Clinical Genor Biopharma Co Ltd, Newbio Therapeutics Inc Breast Neoplasms; Metastatic breast cancer Details
Pertuzumab biosimilar (Shanghai Henlius Biotech) HLX-11 Phase 3 Clinical Shanghai Henlius Biotech Inc Breast Neoplasms; Metastatic breast cancer Details
Anti-HER2 CAR T-cell therapy (Baylor College of Medicine/The Hospital for Sick Children/Texas Children's Hospital/The Methodist Hospital System ) Phase 1 Clinical Baylor College Of Medicine, The Hospital For Sick Children, Texas Children'S Hospital, The Methodist Hosp Research Institute Sarcoma Details
68Ga-anti-HER2 nanobodies (Universite Libre de Bruxelles) Phase 1 Clinical Universite Libre De Bruxelles Breast Neoplasms Details
NeuCeptin NeuCeptin Phase 1 Clinical Neuclone, Serum Institute Of India Ltd Stomach Neoplasms; Breast Neoplasms Details
JSKN-033 JSKN033; JSKN-033 Phase 1 Clinical Alphamab Oncology Solid tumours Details
SSGJ-706 SSGJ-706 Phase 1 Clinical Solid tumours; Lymphoma Details
SSGJ-705 SSGJ-705 Phase 1 Clinical Solid tumours; Neoplasms Details
DZD-1516 DZD-1516 Phase 1 Clinical Dizal (Jiangsu) Pharmaceutical Co Ltd Breast Neoplasms Details
TQB-2102 TQB-2102; TQB2102 Phase 1 Clinical Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group Neoplasms; Breast Neoplasms Details
Zenocutuzumab MCLA-128 Phase 2 Clinical Merus Nv Solid tumours; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
HLX-22 AC-101; HLX-22 Phase 2 Clinical Shanghai Henlius Biotech Inc Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
EO-1001 NT-113; APL-122 Phase 2 Clinical Edison Pharmaceuticals Inc Neoplasms Details
HER.CAR-CMV-specific-CTLs HER.CAR-CMV-specific-CTLs Phase 1 Clinical Baylor College Of Medicine Glioblastoma Details
AMX-3009 Maleate AMX-3009; AMX3009马来酸 Phase 1 Clinical Anrun Medicine Technology (Suzhou) Co Ltd Solid tumours; Stomach Neoplasms; Pancreatic Neoplasms; Breast Neoplasms Details
Autologous-HER2-specific-T-cells Autologous-HER2-specific-T-cells Phase 1 Clinical Baylor College Of Medicine Sarcoma; Brain Neoplasms Details
MP-0274 DARPin-41; SPA-28; CME-114; CME-115; CME-118; CME-119; MP-0274 Phase 1 Clinical Molecular Partners Ag Neoplasms Details
BVAC-B vaccine (Cellid) BVAC-B Phase 1 Clinical Cellid Company Stomach Neoplasms Details
KSP-910638-G KSP-910638G; KSP-910638-G Phase 1 Clinical University Of Michigan Gastrointestinal Neoplasms Details
Trastuzumab biosimilar (Hanwha Biologics) HD-201 Phase 3 Clinical Hanwha Biologics Breast Neoplasms Details
BAY-2927088 BAY-2927088; BAY2927088 Phase 1 Clinical Bayer AG Carcinoma, Non-Small-Cell Lung Details
AIP-303 AIP-303 Phase 2 Clinical Advanced Imaging Projects Breast Neoplasms Details
GB-235 GB-235 Phase 1 Clinical Genor Biopharma Co Ltd Breast Neoplasms Details
Varlitinib Ditosylate SPS-4370; ASLAN-001; ARRY-334543; ARRY-543; QBT-01 Phase 3 Clinical Array Biopharma Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Neoplasms; Pancreatic Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Bile Duct Neoplasms Details
SSGJ-612 SSGJ-612 Phase 1 Clinical Solid tumours Details
GQ-1001 GQ-1001 Phase 2 Clinical GeneQuantum Healthcare (Suzhou) Co Ltd Solid tumours; Biliary Tract Neoplasms; Breast Neoplasms; Metastatic breast cancer Details
Iodine-131-SGMIB anti-HER2 monoclonal antibody [131I]-SGMIB Anti-HER2-VHH1; 131I-SGMIB-anti-HER2-VHH1; Iodine-131-SGMIB-anti-HER2-VHH1; CAM-H2 Phase 2 Clinical Camel-Ids Nv Stomach Neoplasms; Esophageal Neoplasms; Breast Neoplasms Details
AB-201 (Artiva Biotherapeutics) Phase 2 Clinical Artiva Biotherapeutics Inc Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Adenocarcinoma Details
Pertuzumab biosimilar(Biocon) Phase 3 Clinical Biocon Ltd Breast Neoplasms Details
HER2.taNK NK-92/5.28.z Phase 1 Clinical Nantkwest Inc Glioblastoma Details
XZP-KM257 XZP-KM257; KM257/252; KM-257 Phase 1 Clinical Beijing Kangming Bio New Drug Development Co Ltd Solid tumours Details
Pertuzumab biosimilar (Jushi Biopharmaceutical ) SYSA1901; SYSA-1901 Phase 3 Clinical Jushi Biopharmaceutical Co Ltd Breast Neoplasms; Metastatic breast cancer Details
Fencabtagene autoleucel TAC01-HER2 Phase 2 Clinical Triumvira Immunologics Inc Esophageal Neoplasms; Stomach Neoplasms Details
D3L-001 D3L-001 Phase 1 Clinical D3 Bio (Wuxi) Co Ltd Solid tumours; Neoplasms Details
Mefatinib Phase 3 Clinical Suzhou Maitai Bio-Technology Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
trastuzumab biosimilar (Hetero) Ado-Trastuzumab biosimilar (Hetero) Phase 3 Clinical Hetero Drugs Ltd Neoplasms Details
Recombinant anti-HER2 humanized monoclonal antibody complex B-002 Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Breast Neoplasms Details
ALT-P7 HM2-MMAE; ALT-P7 Phase 1 Clinical Alteogen Inc Stomach Neoplasms; Breast Neoplasms Details
XMT-1522 XMT-1522; TAK-522 Phase 1 Clinical Mersana Therapeutics Inc, Adimab LLC Stomach Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
[89Zr]-Df-Trastuzumab Phase 1 Clinical University Of Alabama At Birmingham Solid tumours; Neoplasms; Breast Neoplasms Details
CCT303-406 Phase 1 Clinical Shanghai Sinobioway Sunterra Biotech Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Breast Neoplasms; Sarcoma Details
Coprelotamab GB-221 Phase 3 Clinical Genor Biopharma Co Ltd Breast Neoplasms Details
TY4028 TY-4028; TY4028 Phase 1 Clinical Zhejiang Tongkang Medicine Co Ltd Neoplasms; Carcinoma, Non-Small-Cell Lung Details
99mTc-HPArk2 99mTc-HPArk2; 99-mTc-HPArk-2 Phase 1 Clinical Peking Union Medical College Hospital Breast Neoplasms Details
99mTc-HE3-G3 99mTc-HE3-G3; 99-mTc-HE-3-G-3; 99m-Tc-HE-3-G-3; 99mTc-(HE)3-G3 Phase 1 Clinical Tomsk National Research Medical Center Of The Russian Academy Of Sciences Solid tumours; Breast Neoplasms Details
99mTc-MIRC213 99-mTc-MIRC-213 Phase 1 Clinical Peking Union Medical College Hospital Breast Neoplasms Details
Pertuzumab biosimilar(SL Pharma/Combio) Phase 1 Clinical Beijing Kangming Bio New Drug Development Co Ltd, Beijing Sl Pharmaceutical Co Ltd Inflammatory Breast Neoplasms; Breast Neoplasms; Metastatic breast cancer Details
SPH-5030 SPH-5030 Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Solid tumours Details
IAH-0968 IAH-0968; IAH0968 Phase 2 Clinical SunHo (China) BioPharmaceutical Co Ltd Solid tumours; Biliary Tract Neoplasms; Colorectal Neoplasms Details
Anbenitamab KN-026 Phase 3 Clinical Suzhou Alphamab Co Ltd Biliary Tract Neoplasms; Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Metastatic breast cancer; Lymphoma; Gastrointestinal Neoplasms Details
[14C]-PLB1004 [14C]-PLB1004 Phase 1 Clinical Carcinoma, Non-Small-Cell Lung Details
Anti-CD3-anti-HER2-activated T cells Phase 2 Clinical Transtarget Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Prostatic Neoplasms Details
IBPM002BZ (Inbiopro Solutions) IBPM-002BZ Clinical Inbiopro Solutions Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Colorectal Neoplasms Details
TGFBeta-resistant-HER2-EBV-CTLs TGFBeta-resistant-HER2-EBV-CTLs Phase 1 Clinical Baylor College Of Medicine Neoplasms Details
ETBX-021 ETBX-021 Phase 2 Clinical Nantbioscience Inc, Etubics Corp Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Prostatic Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Autologous AdHER2 dendritic cell vaccine (National Cancer Institute) Phase 1 Clinical National Cancer Institute Neoplasms; Breast Neoplasms; Adenocarcinoma; Neoplasm Metastasis Details
Runimotamab BTRC-4017A; RG-6194; RO-7227780 Phase 1 Clinical F. Hoffmann-La Roche Ltd Solid tumours; Neoplasms Details
Anti-HER2 CAR T-cell therapy (Seattle Children's Hospital) Phase 1 Clinical Seattle Children'S Research Institute Central Nervous System Neoplasms Details
4-1BBz CD19-Her2tG (Seattle Children's Hospital) Phase 1 Clinical Seattle Children'S Hospital Leukemia; Neoplasms; Lymphoma Details
Recombinant anti-HER2 antibody-Tub114 DAC-001; DX126-262 Phase 2 Clinical Hangzhou Dac Biotech Company Ltd Stomach Neoplasms; Carcinoma, Transitional Cell; Breast Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung Details
SNK-02 SNK-02; SNK02 Phase 1 Clinical NKGen Biotech Inc Solid tumours; Neoplasms; Neoplasm Metastasis Details
Sapitinib AZD-8931 Phase 2 Clinical Astrazeneca Pharmaceutical Co Ltd Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Trastuzumab biosimilar(Aprogen/Nichi-Iko) AP-06 Phase 3 Clinical Nichi-Iko Pharmaceutical Co Ltd, Aprogen Breast Neoplasms Details
Trastuzumab biosimilar CMAB-809 Phase 1 Clinical Taizhou Maibo Taike Biotechnology Co Ltd Breast Neoplasms Details
FDA022 Antibody Drug Conjugate Phase 1 Clinical Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd Solid tumours Details
CT-0525 CT-0525 Phase 1 Clinical Carisma Therapeutics Inc Solid tumours Details
Pertuzumab biosimilar(Zydus Cadila) ZRC-3277 Phase 3 Clinical Zydus Cadila Breast Neoplasms Details
Pertuzumab biosimilar (Xuanzhu/SL) KM-118; KM118; XZP-KM118 Phase 3 Clinical Xuanzhu (Shijiazhuang) Biotechnology Co Ltd, Beijing Sl Pharmaceutical Co Ltd Breast Neoplasms Details
SAR-443216 SAR-443216 Phase 1 Clinical Sanofi Solid tumours; Stomach Neoplasms; Neoplasms; Breast Neoplasms; Lung Neoplasms Details
HF-158-K1 HF158K1; HF-158-K1; HF-158K1 Phase 1 Clinical Hangzhou Gaotian Biological Medicine Co Ltd Solid tumours Details
Trastuzumab rezetecan SHR-A1811 Phase 3 Clinical Jiangsu Hengrui Medicine Co Ltd, Suzhou Suncadia Biopharmaceuticals Co Ltd, Shanghai Hengrui Pharmaceutical Co Ltd Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Neoplasms; Salivary Gland Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Metastatic breast cancer; HR-positive breast cancer; Carcinoma, Non-Small-Cell Lung Details
HL-02 HL-02 Phase 3 Clinical Hualan Genetic Engineering Co Ltd Breast Neoplasms Details
EX-101 EX-101; EX101 Phase 1 Clinical Guangzhou Excelmab Inc Solid tumours Details
ZN-A-1041 ZN-A-1041 Phase 1 Clinical Suzhou Zanrong Pharmaceutical Technology Co Ltd Solid tumours; Breast Neoplasms Details
JSKN-003 JSKN-003 Phase 3 Clinical Alphamab Oncology Solid tumours; Neoplasms; Breast Neoplasms Details
XZP-KM501 XZP-KM501; KM-501 Phase 1 Clinical Xuanzhu (Shijiazhuang) Biotechnology Co Ltd Solid tumours; Neoplasm Metastasis Details
HER2/neu peptide vaccine (Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium) Phase 2 Clinical Fred Hutchinson/University Of Washington Cancer Consortium Breast Neoplasms; Breast Neoplasms, Male Details
HER2(EQ)BBzeta/CD19 T cells (City of Hope) Phase 1 Clinical Mustang Bio Inc, City Of Hope National Medical Center Glioma Details
Anvatabart opadotin ARX-788; NCB-001 Phase 3 Clinical Ambrx Inc Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Bile Duct Neoplasms; Metastatic breast cancer Details
Recombinant anti-HER2 subdomain II humanized monoclonal antibody(Livzon) LZM-005 Phase 1 Clinical Livzon Pharmaceutical Group Inc Breast Neoplasms Details
Pertuzumab biosimilar (CinnaGen) Phase 3 Clinical Cinnagen Breast Neoplasms Details
AE-37/GP-2 vaccine AE-37 (Generex Biotechnology Corporation) Phase 2 Clinical Generex Biotechnology Corp Triple Negative Breast Neoplasms; Breast Neoplasms Details
I-025-A I-025-A Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Breast Neoplasms Details
Multiple 4SCAR-T Cell Therapy (Shenzhen Geno-Immune Medical Institute) Phase 2 Clinical Shenzhen Geno-Immune Medical Institute Breast Neoplasms Details
Epertinib S-222611 Phase 2 Clinical Shionogi & Co Ltd Neoplasms Details
99mTc-MIRC208 Clinical Beijing Cancer Hospital Neoplasms Details
Anti-CD3 and anti-HER2 BiTE-expressing T cell (MedImmune) Phase 2 Clinical University Of Michigan, Huazhong University Of Science And Technology, University Of Virginia Cancer Center, Medimmune Breast Neoplasms Details
HER-2 Specific CAR T Cell Phase 1 Clinical Pediatric Brain Tumor Consortium (Pbtc), St. Jude Children'S Research Hospital Ependymoma Details
99m-Tc labeled anti-HER2 single domain antibody (NanoMab) 99mTc-NM-02 Phase 1 Clinical Nanomab Technology Ltd Breast Neoplasms Details
Cinrebafusp alfa PRS-343 Phase 2 Clinical Pieris Pharmaceuticals Solid tumours; Stomach Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms Details
FCN-411 FCN-411 Phase 2 Clinical Shanghai Fosun Pharmaceutical (Group) Co Ltd Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Trastuzumab imbotolimod BDC-1001 Phase 2 Clinical Bolt Biotherapeutics Inc Solid tumours; Esophageal Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms Details
IBI-354 IBI-354 Phase 2 Clinical Innovent Biologics(Suzhou) Co Ltd Solid tumours Details
ACE-1702 ACE-1702 Phase 1 Clinical Acepodia Taiwan Subsidiary Solid tumours; Stomach Neoplasms; Metastatic breast cancer; Neoplasm Metastasis Details
Zongertinib BI-1810631 Phase 1 Clinical C.H. Boehringer Sohn Ag & Co. Kg Solid tumours; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
Recombinant Humanized Anti-Human Epidermal Growth Factor Receptor Monoclonal Antibody and the Dolastatins Derivative DUO5 Conjugated ZV0203; ZV203; ADC2122; ADC 2122 Phase 1 Clinical Zhejiang Hisun Pharmaceutical Co Ltd, Zhejiang Zova Biotherapeutics Inc, Concortis Biosystems Corp Solid tumours Details
SNC109 SNC109; SNC-109 Phase 1 Clinical Shanghai Simnova Biotechnology Co Ltd Glioblastoma Details
KSP-QRH-E3-IRDye800 Phase 1 Clinical University Of Michigan Cholangiocarcinoma Details
Anti-HER2-CAR-T Cells Therapy(Simcere Pharmaceutical) Phase 1 Clinical China Medical University, China Solid tumours Details
ORIC-114 ORIC-114; VRN-07 Phase 2 Clinical Voronoi Inc Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
HER2/Neu GP2 vaccine(Greenwich LifeSciences Inc/NuGenerex Immuno Oncology) GLSI-100 Phase 3 Clinical Antigen Express Inc, Norwell Inc Breast Neoplasms Details
KY-1701 KY-1701 Phase 1 Clinical Jiangsu Kanion Pharmaceutical Co Ltd Breast Neoplasms Details
Recombinant anti-HER2 humanized monoclonal antibody (Shenzhen Main Luck Pharmaceuticals) Phase 1 Clinical Shenzhen Main Luck Pharmaceuticals Inc Breast Neoplasms Details
IMM-2902 IMM-2902 Phase 2 Clinical ImmuneOnco Biopharmaceuticals (Shanghai) Co Ltd Solid tumours; Stomach Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Lung Neoplasms Details
Zanidatamab zovodotin ZW-49 Phase 1 Clinical Zymeworks Inc Neoplasms Details
anti-HER2 ADC (Pfizer) PF-06804103 Phase 2 Clinical Pfizer Inc Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms Details
TT-16 TT-16 Phase 1 Clinical Tessa Therapeutics Ltd Solid tumours Details
Recombinant anti-HER2 humanized HuA21 monoclonal antibody(Hankemab) Phase 1 Clinical Hefei Hankemab Biotechnology Co Ltd Solid tumours Details
Trastuzumab biosimilar (Hualan Biological Engineering) Phase 1 Clinical Hualan Genetic Engineering Co Ltd Stomach Neoplasms; Breast Neoplasms Details
[18F]GE-226 GE-226-[18F]; Fluorine-18-GE-226; [18F]GE-226 Affibody Ab Details
Recombinant anti-HER2 humanized monoclonal antibody (Shanghai Institute of Biological Products) SIBP-01 Phase 3 Clinical Shanghai Institute Of Biological Products Co Ltd Stomach Neoplasms; Breast Neoplasms Details
NJH-395 NJH-395 Phase 1 Clinical Novartis Pharma Ag Neoplasms Details
SHR-A1201 SHR-A1201 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Breast Neoplasms Details
Trastuzumab biosimilar (BioXpress) BXT-2318; BX-2318 Clinical Bioxpress Therapeutics Sa Stomach Neoplasms; Metastatic breast cancer Details
Sirotinib Maleate XZP-5491 Phase 1 Clinical Shandong Xuanzhu Pharmaceutical Technology Co Ltd Stomach Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung Details
DF-1001 DF-1001 Phase 2 Clinical Dragonfly Therapeutics Llc Solid tumours Details
Trastuzumab vedotin MRG-002 Phase 3 Clinical Shanghai Miracogen Inc Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma, Transitional Cell; Breast Neoplasms; Bile Duct Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
Fidasimtamab IBI-315 Phase 1 Clinical Hanmi Pharmaceutical Co Ltd, Innovent Biologics(Suzhou) Co Ltd Solid tumours; Neoplasms Details
NIP-142 NIP-142 Phase 1 Clinical National Institutes Of Pharmaceutical Research And Development Co Ltd Carcinoma, Non-Small-Cell Lung Details
Recombinant anti-HER2 domain II humanized monoclonal antibody (Qilu Pharmaceutical) Phase 1 Clinical Qilu Pharmaceutical Co Ltd Breast Neoplasms Details
PLB-1004 PLB-1004 Phase 3 Clinical Carcinoma, Non-Small-Cell Lung Details
KMHH-03 KMHH-03; KMHH03 Phase 1 Clinical Beijing Kangming Haihui Biological Technology Co Ltd Breast Neoplasms Details
BL-M07D1 BLM07D1 Phase 2 Clinical Sichuan Baili Pharmaceutical Co Ltd Solid tumours; Neoplasms; Breast Neoplasms; Genital Neoplasms, Female; Urogenital Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
BAY-2701438 BAY-2701438 Phase 1 Clinical Bayer AG Neoplasms Details
Tesevatinib XL-647; KD-020; KD-019; EXEL-7647 Phase 2 Clinical Exelixis Inc Glioblastoma; Neoplasms; Brain Neoplasms; Breast Neoplasms; Polycystic Kidney, Autosomal Dominant; Brain metastases; Polycystic Kidney, Autosomal Recessive; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
HER2 cancer vaccine (BioLife Science) PEV-6; PEV-6A; IMU-131 Phase 2 Clinical Pevion Biotech Ltd Esophageal Neoplasms; Stomach Neoplasms; Adenocarcinoma; Gastrointestinal Neoplasms Details
TPIV-100 (TapImmune) TPIV-100 Phase 2 Clinical Mayo Clinic Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Breast Neoplasms, Male Details
BC-004 BC-004 Phase 1 Clinical Shandong Buchang Pharmaceuticals Co Ltd Solid tumours; Breast Neoplasms Details
Tarloxotinib Bromide PR-610; TH-4000; SN-33999 Phase 2 Clinical Threshold Solid tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Non-Small-Cell Lung Details
14C-labeled poziotinib Phase 1 Clinical Spectrum Pharmaceuticals Solid tumours Details
HER2 Targeted HypoSti.CAR-T Cells(Chinese PLA General Hospital) Phase 2 Clinical Pla General Hospital, Fudan University Solid tumours Details
IBPM003TZ (Inbiopro Solutions) IBPM-003TZ Clinical Inbiopro Solutions Breast Neoplasms Details
PB-357 PB-357 Phase 1 Clinical Pfizer Inc Neoplasms Details
BCD-147 BCD-147 Phase 1 Clinical Biocad Details
Anti-HER2 monoclonal antibody-MCC-DM1 conjugate (Shanghai Pharma) B-003 (Shanghai Pharma) Phase 1 Clinical Shanghai Crosslink Pharmaceutical R & D Co Ltd, Shanghai Pharmaceuticals Holding Co Ltd Breast Neoplasms Details
Dual-targeting HER2 and PD-L1 CAR-T Cell Therapy (Sichuan University) Phase 1 Clinical Sichuan University Peritoneal Neoplasms; Pleural Effusion, Malignant Details
Pertuzumab biosimilar(Hisun Pharm) HS-627; HS627 Phase 3 Clinical Zhejiang Hisun Pharmaceutical Co Ltd, Beijing Mabworks Biotech Co Ltd Breast Neoplasms Details
Pertuzumab biosimilar(EirGenix) EG-1206A; EG-1206-A Phase 1 Clinical Eirgenix Inc Breast Neoplasms Details
MBS-301 MBS-301 Phase 1 Clinical Beijing Mabworks Biotech Co Ltd Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
Pirotinib Hydrochloride KBP-5209 Phase 2 Clinical Shandong Xuanzhu Pharmaceutical Technology Co Ltd Solid tumours; Breast Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
MB-103 MB-103 Phase 1 Clinical Mustang Bio Inc, City Of Hope National Medical Center Glioblastoma; Brain metastases Details
JRF-103 JRF103; JRF-103 Phase 2 Clinical Shenzhen Jinrui Foundation Biotechnology Co Ltd Solid tumours Details
GQ-1005 GQ-1005; GQ1005 Phase 1 Clinical GeneQuantum Healthcare (Suzhou) Co Ltd Solid tumours; Neoplasms Details
Larotinib Mesylate Z-650 Phase 3 Clinical Guangdong Dongyangguang Pharmaceutical Co Ltd Solid tumours; Esophageal Neoplasms; Pancreatic Neoplasms; Esophageal Squamous Cell Carcinoma Details
XZP-5209 XZP-5209 Phase 1 Clinical Xuanzhu (Shijiazhuang) Biotechnology Co Ltd Carcinoma, Non-Small-Cell Lung Details
M-802(Wuhan Yzy Biopharma/CSPC Pharmaceutical) M-802 Phase 1 Clinical Wuhan Yzy Biopharma Co Ltd, CSPC Pharmaceutical Group Ltd Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
ORM-5029 ORM-5029 Phase 1 Clinical Orum Therapeutics Inc Solid tumours; Breast Neoplasms Details
Trastuzumab monomethyl auristatin F FS-1502; LCB14-0110; LCB-14-0110 Phase 3 Clinical Legochembio Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung Details
BAY-2701439 BAY-2701439 Phase 1 Clinical Bayer AG Neoplasms Details
Recombinant human ErbB3 fragment vaccine (Zensun) rhErbB3-f Phase 1 Clinical Zensun (Shanghai) Sci&Tech Co Ltd Neoplasms Details
Selatinib Ditosilate QLNC-120 Phase 2 Clinical Qilu Antibiotics (Linyi) Pharmaceutical Co Ltd, Qilu Pharmaceutical Co Ltd Breast Neoplasms Details
99mTc-DARPinG3 99mTc-DARPinG3; 99mTc-DARPinG-3 Clinical Tomsk National Research Medical Center Of The Russian Academy Of Sciences Breast Neoplasms Details
Neptinib Di-P-methylbenzenesulfonate Phase 1 Clinical Shenzhen Neptunus Pharmaceutical Research Institute Co Ltd Stomach Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
FT-825 ONO-8250; FT-825 Phase 1 Clinical Fate Therapeutics Inc Solid tumours Details
Zanidatamab ZW-25 Phase 3 Clinical Zymeworks Inc Biliary Tract Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Bile Duct Neoplasms; Esophageal adenocarcinoma; Endometrial Neoplasms; Carcinosarcoma; Gastrointestinal Neoplasms Details
HER2/neu cancer vaccine (University of Washington/Corixa/GSK) Phase 2 Clinical University Of Washington Ovarian Neoplasms; Breast Neoplasms; Lung Neoplasms; Breast Neoplasms, Male Details
IKS014 IKS014; IKS-014 Phase 1 Clinical Iksuda Therapeutics Inc Stomach Neoplasms; Esophageal Neoplasms; Digestive System Neoplasms; Breast Neoplasms; Gastrointestinal Neoplasms Details
89Zr-ss-Pertuzumab Phase 1 Clinical Genentech Inc Breast Neoplasms; Metastatic breast cancer Details
AU-105 AU-105 Phase 2 Clinical Aurora Biopharma Glioblastoma Details
Gancotamab MM-302 Phase 2 Clinical Merrimack Pharmaceuticals Inc Ovarian Neoplasms; Breast Neoplasms Details
Pertuzumab biosimilar (Hengrui Pharma) SHR-1309 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Metastatic breast cancer Details
Allitinib Tosylate AST-6; ALS-1306; AST-1306 Phase 2 Clinical Shanghai Allist Pharmaceutical Technology Co Ltd Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
MX-402 MX-402 Phase 1 Clinical Medvax Technologies Stomach Neoplasms Details
DP-303c DP-303c; DP303c Phase 3 Clinical CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co Ltd Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Salivary Gland Neoplasms; Neoplasms; Breast Neoplasms; Metastatic breast cancer Details
HER-2/Neu pulsed DC1 vaccine (University of Pennsylvania) Phase 1 Clinical University Of Pennsylvania, National Cancer Institute Breast Neoplasms Details
PM-3002 PM-3002 Phase 1 Clinical Biotheus Inc Details
Trastuzumab biosimilar (NeuClone/Serum Institute of India) Phase 1 Clinical Serum Institute Of India Ltd, Neuclone Stomach Neoplasms; Breast Neoplasms Details
RG-6148 RG-6148; DHES-0815A Phase 1 Clinical F. Hoffmann-La Roche Ltd Breast Neoplasms Details
TAS-2940 TAS-2940 Phase 1 Clinical Taiho Oncology Inc Solid tumours; Glioblastoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
YH-32367 ABL105; YH-32367 Phase 2 Clinical Abl Bio Inc Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
DB-1303 DB-1303; BNT323 Phase 3 Clinical Duality Biologics Co Ltd Solid tumours; Breast Neoplasms; Metastatic breast cancer; Neoplasm Metastasis Details
Trastuzumab biosimilar (United BioPharma) UB-921 Phase 1 Clinical United Biopharma Inc Breast Neoplasms Details
CT-0508 CT-0508 Phase 1 Clinical Carisma Therapeutics Inc Solid tumours Details
BAT-1006 BAT-1006 Phase 1 Clinical Bio-Thera Solutions Ltd Solid tumours Details
BB-1701 BB-1701 Phase 2 Clinical Bliss Biopharmaceutical (Hangzhou) Co Ltd Solid tumours; Stomach Neoplasms; Carcinoma, Transitional Cell; Breast Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung Details
TQB-2930 TQB-2930 Phase 1 Clinical Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group Neoplasms; Breast Neoplasms Details

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