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Your Position: Home > Protein > HLA-A*3001 & B2M & KRASG12V (VVGAVGVGK) > HLV-HA2H7

APC-Labeled Human HLA-A*30:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein

  • Source
    APC-Labeled Human HLA-A*30:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein(HLV-HA2H7) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*30:01) & Ile 21 - Met 119 (B2M) & VVGAVGVGK peptide (Accession # AAA70162.1 (HLA-A*30:01) & P61769 (B2M) & VVGAVGVGK).
    Predicted N-terminus: Gly 25 & Ile 21
  • Molecular Characterization

    APC-Labeled Human HLA-A*30:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein is assembled by biotinylated monomer and APC-labeled streptavidin.

    Biotinylated Human HLA-A*30:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. Biotinylated Human HLA-A*30:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

  • Conjugate


    Excitation Wavelength: 640 nm

    Emission Wavelength: 661 nm

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 1% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A*3001 KRASG12V (VVGAVGVGK) complex protein is a complex of HLA-A*3001 of the MHC Class I, B2M, and VVGAVGVGK peptide of the KRASG12V.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $396.00

Price(USD) : $2280.00

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