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Your Position: Home > Antibody > CD45R > HGS-S248

Recombinant Monoclonal Anti-CD45R Antibody, Mouse (4C4)

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  • Background
    CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling.
  • Host Species

    Mouse

  • Clone

    4C4

  • Application

    IHC

  • Property
    1:500
  • State
    Liquid
  • Positive Control
    Human Tonsil Tissues
  • Clonality
    Monoclonal
  • Synonym
    CD45R
  • Research Field
    Cancer Drug Targets
  • Source
    Mouse
  • Isotype
    IgG
  • Storage
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Typical Data
Control Sample
 CD45R CONTROL SAMPLE

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S248 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Cancer Sample
 CD45R CANCER SAMPLE CD45R CANCER SAMPLE CD45R CANCER SAMPLE

Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S248 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $130.00

Price(USD) : $523.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:3 Details
  • Latest Research Phase:Phase 3 Clinical

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