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Your Position: Home > Integrin alpha 11 beta 1

Integrin alpha 11 beta 1

Brief Information

Name:Leukocyte adhesion glycoprotein LFA-1 alpha
Target Synonym:Integrin, Alpha L (Antigen CD11A (P180), Lymphocyte Function-Associated Antigen 1; Alpha Polypeptide),Leukocyte adhesion glycoprotein LFA-1 alpha chain,ITGAL,LFA-1A,Integrin Subunit Alpha L,CD11 antigen-like family member A,Integrin, Alpha L (Antigen CD11A (P180), Lymphocyte Function-Associated Antigen 1,Alpha Polypeptide),Lymphocyte Function-Associated Antigen 1, Alpha Polypeptide,CD11A,Integrin Gene Promoter,Antigen CD11A (P180),LFA-1 Alpha,LFA-1,LFA1A,CD11a Antigen,Integrin alpha-L,Leukocyte
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
IT1-C53W3 Cynomolgus Cynomolgus Integrin alpha 11 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free
IT1-C53W3-structure
IT1-C53W3-sds
IT1-C52W9 Canine Canine Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free
IT1-C52W9-structure
IT1-C52W9-sds
IT1-M52W5 Mouse Mouse Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free
IT1-M52W5-structure
IT1-M52W5-sds
IT1-H52W3 Human Human Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free
IT1-H52W3-structure
IT1-H52W3-sds
ACRO Quality

Part of Bioactivity data

IT1-C52W9-ELISA
Integrin alpha 11 beta 1 ELISA

Immobilized Native Human Collagen I protein at 10 μg/mL (100 μL/well) can bind Canine ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-C52W9) with a linear range of 0.078-5 μg/mL (QC tested).

Protocol
IT1-C53W3-ELISA
Integrin alpha 11 beta 1 ELISA

Immobilized Native Human Collagen IV Protein at 10 μg/mL (100 μL/well) can bind Cynomolgus ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-C53W3) with a linear range of 0.156-1.25 μg/mL (QC tested).

Protocol

Synonym Name

Integrin alpha 11 beta 1,ITGA11&ITGB1

Background

Integrin alpha 11 beta 1 is a receptor for collagen. The alpha11 cDNA encodes a mature protein with a large 1120-residue extracellular domain that contains an I-domain of 207 residues and is linked by a transmembrane domain to a short cytoplasmic domain of 24 amino acids. The deduced alpha11 protein shows the typical structural features of integrin alpha-subunits and is similar to a distinct group of alpha-subunits from collagen-binding integrins.

Clinical and Translational Updates

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