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| Project Name | Modality | Therapeutic Area | Indications | Stage | Right Available |
| AXL inhibitor | Small molecule | Oncology/Cancer | STK11_mut NSCLC,other cancers | Phase I | Global |
| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| AXL-H82F9 | Human | Biotinylated Human AXL Protein, Fc,Avitag™ (MALS verified) |  |
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| AXL-H5253 | Human | Human Axl Protein, Fc Tag (MALS verified) |  |
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| AXL-C52H3 | Cynomolgus | Cynomolgus Axl Protein, His Tag |  |
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| AXL-H5226 | Human | Human Axl Protein, His Tag (SPR verified) |  |
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Human Axl, Fc Tag (Cat. No. AXL-H5253) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human GAS6, His Tag (Cat. No. GA6-H5249) with an affinity constant of 1.23 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Gilteritinib Fumarate | ASP-2215; 66D-92MGC8M (UNII code); ASP-2215 hemifumarate | Approved | Astellas Pharma Inc | Xospata | Mainland China | Leukemia, Myeloid, Acute | Astellas Pharmaceutical (China) Co Ltd | 2018-09-21 | Solid tumours; Renal Insufficiency; Hepatic Insufficiency; Leukemia, Myeloid, Acute; Carcinoma, Non-Small-Cell Lung | Details |
| Cabozantinib S-malate | XL-184; BMS-907351 | Approved | Exelixis Inc | Cometriq, Cabometyx | Japan | Carcinoma, Renal Cell | Takeda | 2012-11-29 | Osteosarcoma; Thyroid Neoplasms; Gliosarcoma; Colorectal Neoplasms; Peritoneal Neoplasms; Bile Duct Neoplasms; Hepatic Insufficiency; Astrocytoma; Breast Neoplasms; Sarcoma, Ewing; Lymphoma; Carcinoma, Adenosquamous; Adenocarcinoma, Clear Cell; Sarcoma, Clear Cell; Medullary thyroid cancer (MTC); Cholangiocarcinoma; Prostatic Neoplasms; Neurofibroma, Plexiform; Urethral Neoplasms; Carcinoma, Neuroendocrine; Meningioma; Carcinoma, Non-Small-Cell Lung; Paraganglioma; Melanoma; Carcinoma, Endometrioid; Thyroid Cancer, Papillary; Adenocarcinoma; Neoplasms, Germ Cell and Embryonal; Carcinoma, Hepatocellular; Neuroblastoma; Glioma; Leukemia, Myeloid, Acute; Carcinoma, Squamous Cell; Endometrial Neoplasms; Lung Neoplasms; Sarcoma, Alveolar Soft Part; Uterine Neoplasms; Fallopian Tube Neoplasms; Carcinoid Tumor; Neurofibromatoses; Seminoma; Carcinoma, Transitional Cell; Glioblastoma; Rejection of liver transplantation; Carcinoma, Merkel Cell; Hepatoblastoma; Pain; Pheochromocytoma; Neoplasms; Carcinoma, Renal Cell; B | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| NP-01 (Shijiazhuang No.4 Pharmaceutical/Nanjing Nadingfei Medical Technology) | NP-01 | Phase 1 Clinical | Shijiazhuang No 4 Pharmaceutical Co Ltd, Nanjing Nadingfei Pharmaceutical Technology Co Ltd | Liver Neoplasms; Solid tumours; Stomach Neoplasms; Lung Neoplasms | Details |
| AGX-0073 | AGX-0073 | Phase 1 Clinical | Shanghai Aojian Biological Technology Co Ltd | Solid tumours | Details |
| NP-107 | NP107; NP-107 | Phase 1 Clinical | Shanghai Nawei Biotechnology Co Ltd | Solid tumours | Details |
| BPI-9016 | BPI-9016; BPI-9016M | Phase 1 Clinical | Betta Pharmaceuticals Co Ltd | Solid tumours; Carcinoma, Non-Small-Cell Lung | Details |
| ONO-7475 | ONO-7475 | Phase 2 Clinical | Ono Pharmaceutical Co Ltd | Leukemia, Myeloid, Acute | Details |
| Tilvestamab | BGB-149 | Phase 1 Clinical | Bergenbio | Ovarian Neoplasms | Details |
| Enapotamab vedotin | AXL-107-MMAE | Phase 2 Clinical | Seattle Genetics Inc, Genmab A/S | Ovarian Neoplasms; Sarcoma; Endometrial Neoplasms; Thyroid Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Melanoma | Details |
| XZB-0004 | SLC-391; XZB-0004 | Phase 1 Clinical | Solid tumours; Hematologic Neoplasms; Foodborne Diseases; Carcinoma, Non-Small-Cell Lung | Details | |
| Butylidenephthalide | HK-001; LF-001 (Everfront Biotech); NSC-325307; BDPH | Phase 2 Clinical | Everfront Biotech Co Ltd | Glioma; Amyotrophic Lateral Sclerosis | Details |
| Glesatinib | 7Q29OXD98N; MG-90265H9; MG-90265gly; MG-90265; MG-90265X; MGCD-265 | Phase 2 Clinical | Mirati Therapeutics Inc | Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| INCB-081776 | INCB-81776; INCB-081776 | Phase 1 Clinical | Incyte Corp | Solid tumours; Neoplasms | Details |
| Dubermatinib | TP-0903 | Phase 2 Clinical | Sumitomo Dainippon | Ovarian Neoplasms; Solid tumours; Neoplasms; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Melanoma; Carcinoma, Non-Small-Cell Lung | Details |
| Bemcentinib | R-428; BGB-324 | Phase 2 Clinical | Rigel Pharmaceuticals Inc | Coronavirus Disease 2019 (COVID-19); Inflammatory Breast Neoplasms; Triple Negative Breast Neoplasms; Myelodysplastic Syndromes; Adenocarcinoma of Lung; Pancreatic Neoplasms; Mesothelioma; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| KC1036 | KC1036; KC-1036 | Phase 2 Clinical | Beijing Konruns Pharmaceutical Co Ltd | Solid tumours; Hematologic Neoplasms; Digestive System Neoplasms; Neoplasm Metastasis | Details |
| Q-702 | Q-702 | Phase 2 Clinical | Qurient Co Ltd | Solid tumours; Liver Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Neoplasm Metastasis; Uterine Cervical Neoplasms | Details |
| FC-084-CSA | FC-084-CSA; FC084CSA | Phase 1 Clinical | Zhongshan Yinuo Weishen New Drug Research and Development Co Ltd | Solid tumours | Details |
| PF-07265807 | PF-07265807 | Phase 1 Clinical | Solid tumours; Neoplasm Metastasis | Details | |
| TT-00973 | TT-00973 | Phase 1 Clinical | TransThera Sciences (Nanjing) Inc | Solid tumours | Details |
| HH-30134 | HH-30134 | Phase 1 Clinical | ShangHai HaiHe Biopharma Co Ltd | Solid tumours; Neoplasms | Details |
| Ningetinib Tosylate | CT-053-PTSA; CT-053 | Phase 2 Clinical | Hec Pharm Co Ltd | Solid tumours; Intestinal Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Lung Neoplasms; Leukemia, Myeloid, Acute; Carcinoma, Non-Small-Cell Lung | Details |
| CCT301-38 | CCT301-38; CCT301-38 AXL | Phase 2 Clinical | F1 Oncology, Bioatla | Carcinoma, Renal Cell; Rhinitis, Allergic, Seasonal | Details |
| Mipasetamab uzoptirine | ADCT-601; BGB-601 | Phase 1 Clinical | Adc Therapeutics Sa | Solid tumours; Neoplasms | Details |
| Mecbotamab vedotin | BA-3011; BA3011; BA 3011 | Phase 2 Clinical | Bioatla | Solid tumours; Leiomyosarcoma; Ovarian Neoplasms; Sarcoma, Synovial; Liposarcoma; Sarcoma; Osteosarcoma; Sarcoma, Ewing; Carcinoma, Non-Small-Cell Lung; Melanoma | Details |
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