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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > HGF R

HGF R

Brief Information

Name:Hepatocyte growth factor receptor
Target Synonym:EC 2.7.10,EC:2.7.10.1,HGF receptor,HGF/SF receptor,Hepatocyte growth factor receptor,Tyrosine-protein kinase Met,MET,SF receptor,Scatter factor receptor,MET Proto-Oncogene, Receptor Tyrosine Kinase,Proto-Oncogene C-Met,Met Proto-Oncogene,EC 2.7.10.1,DFNB97,AUTS9,RCCP2,C-Met,HGFR,Proto-Oncogene Proteins c-met
Number of Launched Drugs:7
Number of Drugs in Clinical Trials:44
Lastest Research Phase:Approved

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Part of Bioactivity data

MET-C5256-ELISA
Canine HGF R,Fc TagCanine HGF R,Fc Tag (Cat. No. MET-C5256) ELISA bioactivity

Immobilized Canine HGF R,Fc Tag (Cat. No. MET-C5256) at 5 μg/mL (100 μL/well) can bind Human HGF, His Tag (Cat. No. HGF-H52H3) with a linear range of 2-16 ng/mL (QC tested).

MET-C5256-MALS-HPLC
Canine HGF R,Fc Tag (Cat. No. ) MALS images

The purity of Canine HGF R,Fc Tag (Cat. No. MET-C5256) is more than 90% and the molecular weight of this protein is around 290-320 kDa verified by SEC-MALS.

Bioactivity-ELISA
Canine HGF R,Fc TagCanine HGF R,Fc Tag (Cat. No. MET-C5256) ELISA bioactivity

Immobilized Canine HGF R,Fc Tag (Cat. No. MET-C5256) at 5 μg/mL (100 μL/well) can bind Human HGF, His Tag (Cat. No. HGF-H52H3) with a linear range of 2-16 ng/mL (QC tested).

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Synonym Name

MET,AUTS9,HGFR,RCCP2,c-Met

Background

The SARS-CoV-2 Spike S2-coupled Magnetic Beads is produced by coupling biotinylated SARS-CoV-2 spike S2 protein to streptavidin-conjugated magnetic beads. Because Streptavidin (SA) has an extraordinarily high affinity for biotin with a dissociation constant (Kd) on the order of 10-14 mol/L, the biotinylated protein can bind to the SA beads irreversibly. The pre-coupled beads are ready to use for capturing anti-SARS-CoV-2 antibody or ACE2 protein from your sample with high specificity.

Clinical and Translational Updates

Related Molecule

HGF

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Ensartinib Hydrochloride X-396 Approved Xcovery 贝美纳 Mainland China Carcinoma, Non-Small-Cell Lung Betta Pharmaceuticals Co Ltd 2020-11-17 Solid tumours; Lung Neoplasms; Brain metastases; Carcinoma, Non-Small-Cell Lung Details
Savolitinib HMP-504; HMPL-504; HM-5016504; AZD-6094 Approved Hutchison Medipharma Ltd 沃瑞沙, ORPATHYS Mainland China Carcinoma, Non-Small-Cell Lung Hutchison Huangpu Medicine (Shanghai) Co Ltd 2021-06-22 Kidney Neoplasms; Carcinoma, Renal Cell; Stomach Neoplasms; Carcinoma; Esophageal Neoplasms; Kidney Diseases; Neoplasms; Urologic Neoplasms; Lung Neoplasms; Carcinosarcoma; Carcinoma, Non-Small-Cell Lung Details
Cabozantinib S-malate XL-184; BMS-907351 Approved Exelixis Inc Cometriq, Cabometyx Japan Carcinoma, Renal Cell Takeda 2012-11-29 Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Pain; Esophageal Neoplasms; Glioblastoma; Kidney Diseases; Prostatic Neoplasms; Colorectal Neoplasms; Astrocytoma; Hepatic Insufficiency; Thyroid Neoplasms; Carcinoma, Neuroendocrine; Lymphoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
Capmatinib Hydrochloride NVP-INC280-NX; INCB-28060; C2A374O70X; INC-280; INCB-028060 Approved Incyte Corp, Novartis Pharma Ag Tabrecta Japan Carcinoma, Non-Small-Cell Lung Novartis Pharma Ag 2020-05-06 Liver Neoplasms; Solid tumours; Carcinoma; Adenocarcinoma of Lung; Triple Negative Breast Neoplasms; Hepatic Insufficiency; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular; Neoplasm Metastasis Details
Amivantamab JNJ-372; JNJ-61186372 Approved Janssen Global Services Llc, Genmab RYBREVANT EU Carcinoma, Non-Small-Cell Lung Janssen-Cilag International Nv 2021-05-21 Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Crizotinib PF-1066; PF-2341066; PF-02341066; PF-002341066 Approved Pfizer Pharmaceuticals Ltd (China) 赛可瑞, Xalkori United States Lymphoma, Large-Cell, Anaplastic Pf Prism Cv 2011-08-26 Kidney Diseases; Lung Neoplasms; Lymphoma, Large-Cell, Anaplastic; Carcinoma, Non-Small-Cell Lung Details
Tepotinib hydrochloride hydrate EMD-1214063; MSC-2156119; MSC-2156119J Approved Merck Serono テプミトコ, TEPMETKO, Tepmetko United States Carcinoma, Non-Small-Cell Lung Emd Serono Inc 2020-03-25 Solid tumours; Hepatic Insufficiency; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
SAIT-301 SAIT-301 Phase 1 Clinical Samung Medical Centre Neoplasms Details
Emibetuzumab LA-480; LY-2875358 Phase 2 Clinical Eli Lilly And Company Liver Neoplasms; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Esophageal Neoplasms; Lymphoma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung Details
Glumetinib SCC244; HH-SCC244 Phase 2 Clinical Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Greenvalley Pharmaceutical Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
ASLAN-002 ASLAN-002; BMS-777607; BMS-797669 Phase 2 Clinical Bristol-Myers Squibb Company Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
MCLA-129 MCLA-129 Phase 2 Clinical Merus Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Kanitinib CX-1003 Phase 1 Clinical Beijing Konruns Pharmaceutical Co Ltd, Guangzhou Yingsheng Bio Technology Co Ltd Solid tumours; Esophageal Neoplasms; Prostatic Neoplasms Details
Glesatinib MG-90265; MGCD-265; MG-90265X; 7Q29OXD98N; MG-90265H9; MG-90265gly Phase 2 Clinical Mirati Therapeutics Carcinoma, Non-Small-Cell Lung Details
Merestinib 5OGS5K699E; LY-2801653 Phase 2 Clinical Eli Lilly And Company Solid tumours; Biliary Tract Neoplasms; Skin Melanoma; Pancreatic Neoplasms; Microsatellite instability-high cancer; Cholangiocarcinoma; Breast Neoplasms; Lymphoma, Mantle-Cell; Colorectal Neoplasms; Gallbladder Neoplasms; Lymphoma, Non-Hodgkin; Neoplasm Metastasis Details
SAR-125844 SAR-125844 Phase 2 Clinical Sanofi Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Metatinib Trometamol BMS-817378; SIM-817378 Phase 1 Clinical Bristol-Myers Squibb Company Liver Neoplasms; Solid tumours; Stomach Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
CBT-101 CBT-101 Phase 1 Clinical Crown Bioscience Solid tumours Details
AL-2846 AL-2846 Phase 2 Clinical Advenchen Laboratories Nanjing Ltd, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Bone metastases; Liver Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Neurofibroma; Prostatic Neoplasms; Medullary thyroid cancer (MTC); Colorectal Neoplasms; Glioma; Carcinoma, Non-Small-Cell Lung; Neurofibromatosis 1 Details
LMV-12(HE003) LMV-12(HE003) Phase 1 Clinical Nanchang Hongyi Technology Co Ltd Solid tumours Details
S-49076 S-49076 Phase 2 Clinical Servier Glioblastoma; Carcinoma, Non-Small-Cell Lung Details
ABN-401 ABN-401; KDDF-201603-08 Phase 2 Clinical Abion Inc Solid tumours Details
Sym-015 Sym-015 Phase 2 Clinical Symphogen Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
SPH3348 SPH-3348 Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Solid tumours Details
RC-108 RC-108; RC108 Phase 1 Clinical RemeGen Co Ltd Solid tumours Details
Altiratinib DP-5164; DCC-2701; DCC-22701; T-678746713 Phase 1 Clinical Deciphera Solid tumours; Neoplasms Details
JNJ-38877618 OMO-1; JNJ-38877618 Phase 2 Clinical Johnson & Johnson Neoplasms Details
SHR-A1403 SHR-A1403 Phase 1 Clinical Solid tumours Details
Boxitinib Hydrochloride Phase 1 Clinical Hec Pharm Co Ltd Stomach Neoplasms; Carcinoma, Renal Cell; Breast Neoplasms; Glioma; Lung Neoplasms Details
CM-118 CM-118 Phase 1 Clinical Xcovery Carcinoma, Non-Small-Cell Lung Details
GST-HG161 GST-HG161 Phase 1 Clinical Wuxi Apptec Co Ltd, Fujian Cosunter Pharmaceutical Co Ltd Solid tumours; Carcinoma, Hepatocellular Details
AMG-337 AMG-337 Phase 2 Clinical Amgen Inc Solid tumours; Stomach Neoplasms; Sarcoma, Clear Cell; Esophageal adenocarcinoma Details
BPI-9016 BPI-9016; BPI-9016M Phase 1 Clinical Betta Pharmaceuticals Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Sitravatinib MG-516; MG-91516; MGCD-516; IND-155305 Phase 3 Clinical Mirati Therapeutics Solid tumours; Carcinoma; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Neoplasms; Hepatic Insufficiency; Ureteral Neoplasms; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Carcinoma, Hepatocellular Details
Recombinant plasmid-hepatocyte growth factor Pudk-HGF Phase 3 Clinical Academy Of Military Medical Sciences, Wuhan Optical Valley Humanwell Biological Pharmaceutical Co Ltd Ischemia; Peripheral Arterial Disease Details
NP-01 (Shijiazhuang No.4 Pharmaceutical/Nanjing Nadingfei Medical Technology) NP-01 Phase 1 Clinical Shijiazhuang No 4 Pharmaceutical Co Ltd, Nanjing Nadingfei Pharmaceutical Technology Co Ltd Liver Neoplasms; Solid tumours; Stomach Neoplasms; Lung Neoplasms Details
HLX-55 HLX-55; KTN-0216 Phase 1 Clinical Kolltan Solid tumours Details
Pamufetinib TAS-115 Phase 1 Clinical Neoplasms Details
Refanalin ANG-3777; BB-3; SNV-003 Phase 3 Clinical Vifor Pharma Ag, Angion Biomedica Pneumonia; Myocardial Infarction; Coronavirus Disease 2019 (COVID-19); Acute Kidney Injury; Delayed Graft Function Details
Elzovantinib TPX-0022 Phase 1 Clinical Turning Point Therapeutics Inc Solid tumours Details
Anti-cMet SIMPLE Antibody ARGX-111 Phase 1 Clinical Argenx Se Neoplasms Details
c-Met/PD-L1 CAR-T cell (The Second Hospital of Nanjing Medical University) Phase 1 Clinical The Second Hospital Of Nanjing Medical University Carcinoma, Hepatocellular Details
QBH-196 QBH-196 Phase 1 Clinical Shenyang Pharmaceutical University Solid tumours; Stomach Neoplasms Details
Ningetinib Tosylate CT-053; CT-053-PTSA Phase 2 Clinical Hec Pharm Co Ltd Solid tumours; Intestinal Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
LM-061 LM-061 Phase 2 Clinical Shanghai Lixin Pharmaceutical Research and Development Co Ltd Congenital Hyperinsulinism; Solid tumours Details
CKD-702 Phase 1 Clinical Chong Kun Dang Pharmaceutical Corp Carcinoma, Non-Small-Cell Lung Details
Bozitinib CBT-101; CBI-3103; PLB-1001; APL-101 Phase 2 Clinical Beijing Purunao Biotechnology Co Ltd, Crown Bioscience, Cbt, Heng Kang Solid tumours; Kidney Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Glioblastoma; Ganglioglioma; Brain Neoplasms; Lung Neoplasms; Glioma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
HS-10241 HS-10241 Phase 1 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Liver Neoplasms; Solid tumours; Carcinoma; Stomach Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Telisotuzumab vedotin ABBV-399; ABT-399 Phase 3 Clinical Abbvie Inc Solid tumours; Carcinoma, Non-Small-Cell Lung Details
XL-092 XL-092 Phase 1 Clinical Exelixis Solid tumours; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Prostatic Neoplasms; Breast Neoplasms; Colorectal Neoplasms Details
REGN-5093 REGN-5093 Phase 2 Clinical Regeneron Pharmaceuticals Inc Carcinoma, Non-Small-Cell Lung Details
REGN-5093-M114 METxMET-M114; REGN5093-M114 Phase 2 Clinical Regeneron Pharmaceuticals Inc Carcinoma, Non-Small-Cell Lung Details
NDX-1017 NDX-1017; ATH-1017 Phase 2 Clinical M3 Biotechnology Alzheimer Disease; Lewy Body Disease Details
Bafisontamab EMB-01 Phase 2 Clinical Shanghai Epimab Biotherapeutics, Inc Biliary Tract Neoplasms; Liver Neoplasms; Stomach Neoplasms; Carcinoid Tumor; Digestive System Neoplasms; Colorectal Neoplasms; Carcinoma, Hepatocellular; Neoplasm Metastasis; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung Details

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