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Your Position: Home > Amyloid Precursor Protein

Amyloid Precursor Protein

Brief Information

Name:Beta amyloid A4 protein
Target Synonym:Beta-CTF,Amyloid Beta Precursor Protein,Cerebral Vascular Amyloid Peptide,Beta-Amyloid Precursor Protein,Amyloid-Beta A4 Protein,Beta-Amyloid Peptide,Alzheimer Disease,CTFgamma,ABETA,AAA,PN2,Amyloid beta-Peptides,Amyloid intracellular domain 57,APP,Amyloid intracellular domain 59,PN-II,Alpha-secretase C-terminal fragment,AICD-50,S-APP-alpha,A4,S-APP-beta,Alzheimer disease amyloid protein,Abeta40,Gamma-CTF(59),Abeta42,Gamma-CTF(57),Alpha-CTF,Amyloid intracellular domain 50,AID(59),Gamma-CTF(50),A
Number of Launched Drugs:11
Number of Drugs in Clinical Trials:39
Lastest Research Phase:Approved

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Synonym Name

Amyloid Precursor Protein,Alzheimer disease amyloid protein,APP,Amyloid-beta precursor protein

Background

Amyloid precursor protein (APP) is a type 1 membrane protein with an NH2 -terminal extracellular domain and a COOH-terminal cytosolic tail. The amyloid precursor protein (APP) takes a key role in Alzheimer’s disease (AD) pathogenesis. Processing of APP generates that generates the Aβ peptide, whose accumulation is associated with Alzheimer’s disease.

Clinical and Translational Updates

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