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Introduction

bioSeedin, one of the most preeminent asset management, public relations, and financial advisory firms for biotech and pharmaceutical companies in APAC, operates across North America, Europe, and Asia.

The firm provides asset management services via licensing in and out, co-developmental partner sourcing, and project implementation, as well as advising on public relation management, Asia market entry, investment strategy, mergers and acquisitions, and capital raising.

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SN-38 Polymeric Nanoparticle (new formulation)

Preclinical
PH1
PH2
PH3
  • Indications: Solid Tumor (Lung Cancer)
  • Cooperation demands: Global and Regional Out-licensing
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Viscous Gel Temozolomide

Preclinical
PH1
PH2
PH3
  • Indications: Glioblastoma
  • Cooperation demands: license-out or co-development Globally except in CIA
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EED inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: Hematological malignancy and Solid tumors
  • Cooperation demands: License-out or co-development
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ActRIIB inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: Cancer cachexia
  • Cooperation demands: License-out or co-development
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Anti-GCC humanized antibody

Preclinical
PH1
PH2
PH3
  • Indications: Solid Tumor (Colorectal, gastric and esophageal cancers）
  • Cooperation demands: sequence authorization or project transfer
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Active

CCR8 Humanized Antibody

Preclinical
PH1
PH2
PH3
  • Indications: Solid tumor
  • Cooperation demands: sequence authorization or project transfer
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FRα BsAb-ADC

Preclinical
PH1
PH2
PH3
  • Indications: Ovarian cancer
  • Cooperation demands: sequence authorization or project transfer
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B7-H3×CD3 BsAb for solid tumor

Preclinical
PH1
PH2
PH3
  • Indications: Solid tumor
  • Cooperation demands: License-out or co-development
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Active

PD-1×TIGIT BsAb for Advanced solid tumor

Preclinical
PH1
PH2
PH3
  • Indications: Advanced solid tumor
  • Cooperation demands: License-out or co-development
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Active

Her2xCD3 BsAb

Preclinical
PH1
PH2
PH3
  • Indications: HER2+ Cancer
  • Cooperation demands: License-out and co-development
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Active

A2aR/A2bR Antagonist

Preclinical
PH1
PH2
PH3
  • Indications: Advanced/metastatic solid tumors or hematological malignancies
  • Cooperation demands: License-out (Ex-China) or co-development
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Active

GIP/GLP-1/FGF21 Fusion Protein treating NASH, T2DM, Hyperlipoidemia

Preclinical
PH1
PH2
PH3
  • Indications: NASH, T2DM, Hyperlipoidemia
  • Cooperation demands: License-out or co-development the global right
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PI3K/mTOR dual inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: Idiopathic pulmonary fibrosis (IPF) and solid tumor, (FDA ODD）
  • Cooperation demands: License-out or co-development
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HIF-PHs inhibitor for CKD and Renal anemia

Preclinical
PH1
PH2
PH3
  • Indications: CKD and Renal anemia
  • Cooperation demands: License-out or co-development of the global right (except for China)
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NF-kB inhibitor (Novel small molecule drug) for cancer cachexia

Preclinical
PH1
PH2
PH3
  • Indications: Cancer Cachexia
  • Cooperation demands: License-out or co-development the global right
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Oxazolidone (new compounds) antibiotics

Preclinical
PH1
PH2
PH3
  • Indications: bacterial infections caused by specific microbial sensitive strains, such as complex or non-complex skin and skin soft tissue infections, community/hospital acquired pneumonia, vancomycin-resistant enterococcal infections, other bone and joint infections,
  • Cooperation demands: License-out or co-development the global right
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High selective OX1R/OX2R dual inhibitor treating insomnia

Preclinical
PH1
PH2
PH3
  • Indications: Insomnia
  • Cooperation demands: License-out or co-development the global right
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Active

ACC inhibitor treating NASH

Preclinical
PH1
PH2
PH3
  • Indications: NASH
  • Cooperation demands: License-out or co-development the global right
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FXR Agonist

Preclinical
PH1
PH2
PH3
  • Indications: Diabetic kidney disease
  • Cooperation demands: Out licensing global right
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SGLT2 inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: Diabetes
  • Cooperation demands: Out licensing global right
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Active

FXR Agonist

Preclinical
PH1
PH2
PH3
  • Indications: NASH
  • Cooperation demands: License-out or co-development
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Active

XO/URAT1 Dual target inhibitors for HUA

Preclinical
PH1
PH2
PH3
  • Indications: Hyperuricemia (HUA)
  • Cooperation demands: License-out or co-development
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Active

Anti-B7H3 ADC

Preclinical
PH1
PH2
PH3
  • Indications: Broad cancer
  • Cooperation demands: License-out or co-development the global right
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Active

sGC stimulator

Preclinical
PH1
PH2
PH3
  • Indications: Pulmonary arterial hypertension (PAH), Chronic thromboembolic pulmonary hypertension (CTEPH), Heart failure with reduced ejection fraction (HFrEF), Chronic kidney disease (CKD)
  • Cooperation demands: License-out or co-development
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Reversible MAOB Inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: Parkinson's disease
  • Cooperation demands: License-out or co-development
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Active

A SSRI & Partial 5-HT1A Agonist

Preclinical
PH1
PH2
PH3
  • Indications: Depression
  • Cooperation demands: License-out or co-development
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Active

RET high selective inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: NSCLC, Medullary thyroid cancer, Thyroid cancer
  • Cooperation demands: License-out or co-development
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Active

Capsid Assembly Inhibitors for HBV

Preclinical
PH1
PH2
PH3
  • Indications: HBV
  • Cooperation demands: License-out or co-development
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Active

PI3Kδ inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: Hematologic malignancies
  • Cooperation demands: License-out and co-development
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Active

Capsid Assembly Inhibitors for HBV

Preclinical
PH1
PH2
PH3
  • Indications: HBV
  • Cooperation demands: License-out or co-development
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NCE for the treatment of IPF

Preclinical
PH1
PH2
PH3
  • Indications: Idiopathic Pulmonary Fibrosis (IPF)
  • Cooperation demands: License-out or co-development
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Active

FLT3 Inhibition

Preclinical
PH1
PH2
PH3
  • Indications: FLT3-ITD mutation AML
  • Cooperation demands: License-out or co-development
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Active

Anti-Her2 II / Anti-Her2 IV Bi-specific antibody ADC

Preclinical
PH1
PH2
PH3
  • Indications: Solid tumor
  • Cooperation demands: License-out or co-development
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Active

EGFR inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: Esophageal Carcinoma and Pancreatic Cancer
  • Cooperation demands: License-out or co-development for the global right and Clinical development in the US or EU (PK and Phase III)
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5-HT1F agonist

Preclinical
PH1
PH2
PH3
  • Indications: Migraine
  • Cooperation demands: License-out or co-development
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Active

Orexin Receptor Antagonist (OX1R and OX2R)

Preclinical
PH1
PH2
PH3
  • Indications: Insomnia Disorder
  • Cooperation demands: License-out or co-development
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Active

PEGylation CD3 + CD19 bsAb

Preclinical
PH1
PH2
PH3
  • Indications: Autoimmune disease
  • Cooperation demands: License-out or co-development
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Active

DHODH inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: IBD, expanded indication COVID-19
  • Cooperation demands: License-out or co-development
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Active

c-Met/AXL inhibitor

Preclinical
PH1
PH2
PH3
  • Indications: Gastric cancer, solid tumor
  • Cooperation demands: License-out or co-development
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Active

LAG-3 mAb

Preclinical
PH1
PH2
PH3
  • Indications: Advanced solid tumors
  • Cooperation demands: License-out or co-development
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Active

Claudin18.2×CD8+ T bsAb

Preclinical
PH1
PH2
PH3
  • Indications: gastric cancer, pancreatic cancer, lung cancer
  • Cooperation demands: License-out or co-development
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Active

SIRPα×PD-1 bsAb

Preclinical
PH1
PH2
PH3
  • Indications: broad cancer
  • Cooperation demands: License-out or co-development
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Active

TIM3×PD-1 bsAb

Preclinical
PH1
PH2
PH3
  • Indications: Solid Tumor
  • Cooperation demands: License-out or co-development
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Claudin18.2 mAb

Preclinical
PH1
PH2
PH3
  • Indications: Gastric cancer, Pancreatic cancer
  • Cooperation demands: License-out or co-development
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Active

CD40 mAb

Preclinical
PH1
PH2
PH3
  • Indications: Advanced solid tumors
  • Cooperation demands: License-out or co-development
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Active

IL10 / IL10RA mAb

Preclinical
PH1
PH2
PH3
  • Indications: Sepsis/ HLH/ CRS
  • Cooperation demands: License-out or co-development
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Active

CD19+CD37 CAR-T

Preclinical
PH1
PH2
PH3
  • Indications: NHL, Leukemia
  • Cooperation demands: License-out or co-development
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Active

CD47 Monoclonal Antibody

Preclinical
PH1
PH2
PH3
  • Indications: Hematologic tumors, solid tumors
  • Cooperation demands: License-out or co-development
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Active

CD37+CD22 CAR-T

Preclinical
PH1
PH2
PH3
  • Indications: Hematological malignancies (leukemia, multiple myeloma, lymphoma)
  • Cooperation demands: License-out or co-development
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Trop2 ADC

Preclinical
PH1
PH2
PH3
  • Indications: “hard-to-treat” solid tumors (pancreatic, gastric, etc)
  • Cooperation demands: License-out or co-development
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NGF mAb

Preclinical
PH1
PH2
PH3
  • Indications: Cancer pain, chemotherapy-induced neuropathic pain, Kashin-Beck disease, diabetic neuralgia, interstitial cystitis, chronic low back pain.
  • Cooperation demands: License-out or co-development
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Active

B7H3×PD-L1 bsAb

Preclinical
PH1
PH2
PH3
  • Indications: B7H3+ and PD-L1+/low cancer
  • Cooperation demands: License-out or co-development
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CD19 mAb

Preclinical
PH1
PH2
PH3
  • Indications: Autoimmune diseases/ B cell malignancies
  • Cooperation demands: License-out or co-development
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Active

BAFFR×CD3 bsAb

Preclinical
PH1
PH2
PH3
  • Indications: B cell malignancies/ autoimmune diseases
  • Cooperation demands: License-out or co-development
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Active

TIGIT-Fc protein

Preclinical
PH1
PH2
PH3
  • Indications: Advanced solid tumors, especially those with high expression of CD155
  • Cooperation demands: Project authorization, transfer or co-development.
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Anti-PD-L1 / TIGIT bispecific antibody

Preclinical
PH1
PH2
PH3
  • Indications: NSCLC, SCLC, multiple myeloma, liver cancer, triple negative breast cancer, pancreatic cancer, etc.
  • Cooperation demands: Project authorization, transfer or co-development.
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Antagonizing TSP1/CD36 Polypeptide Blocking the activation of TGF-β1

Preclinical
PH1
PH2
PH3
  • Indications: Progressive Fibrosis Interstitial Lung Disease (PF-ILD), Solid Tumor.
  • Cooperation demands: Out-licensing outside the Great China
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PD-1/CD80 bispecific antibody

Preclinical
PH1
PH2
PH3
  • Indications: Solid tumors such as lung cancer, gastric carcinoma, esophagus cancer, cervical cancer.
  • Cooperation demands: Project transfer or co-development. (the project’s company is in the startup stage and seek external cooperation to accelate drug research and development.)
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Target 4-1BB monoclonal antibody

Preclinical
PH1
PH2
PH3
  • Indications: Tumors such as breast cancer, bladder cancer, NSCLC,DLBCL.
  • Cooperation demands: Project authorization, transfer or co-development. (project’s company is seeking for external cooperation to accelate drug research and development.)
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Anti-LAG-3 monoclonal antibody

Preclinical
PH1
PH2
PH3
  • Indications: Tumors such as melanoma, non-small cell lung cancer,liver cancer, gastric carcinoma
  • Cooperation demands: Project authorization, transfer or co-development. (project’s company is seeking for external cooperation to accelate drug research and development.)
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Anti-TIM-3 monoclonal antibody

Preclinical
PH1
PH2
PH3
  • Indications: Tumors such as lung cancer,liver cancer, gastric carcinoma, cervical cancer, prostate cancer.
  • Cooperation demands: Project authorization, transfer or co-development. (project’s company is seeking for external cooperation to accelate drug research and development.)
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