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Your Position: Home > TME Relevant Pathway > DKK-2 > DK2-H52H3

Human DKK-2 Protein, His Tag

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Source
    Human DKK-2 Protein, His Tag(DK2-H52H3) is expressed from human 293 cells (HEK293). It contains AA Lys 34 - Ile 259 (Accession # Q9UBU2 ).
    Predicted N-terminus: Lys 34
  • Molecular Characterization
    DKK-2 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 27 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. 
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $210.00

Price(USD) : $1260.00

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Datasheet & Documentation

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DMF (Drug Master File)

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