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Your Position: Home > Cell Therapy Antibodies > CD3 epsilon > CDE-M525a

Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag™ (Clone: OKT3), Ultra-low endotoxin (MALS verified)

  • Source
    Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3) (CDE-M525a) is recombinantly produced from human 293 cells (HEK293).
  • Isotype
    Mouse IgG2a / kappa
  • Specificity
  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Endotoxin
    Less than 0.002 EU per μg by the LAL method.
  • Sterility

    The sterility testing was performed by membrane filtration method described in USP <71> and Eur. Ph. 2.6.1.

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    For long term storage, the product should be stored at liquid state at 4°C.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. 4°C for 12 months in liquid state;
    2. The product MUST be stored at 4°C upon receipt.
  • Shipping
    This product is supplied and shipped as sterile liquid solution with blue ice, please inquire the shipping cost.
SDS-PAGE
Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3) (Cat. No. CDE-M525a) SDS-PAGE gel

Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3) (Cat. No. ) MALS images

The purity of Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3) (Cat. No. CDE-M525a) is more than 95% and the molecular weight of this protein is around 140-160 kDa verified by SEC-MALS.

Bioactivity-ELISA
Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3)Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3) (Cat. No. CDE-M525a) ELISA bioactivity

Immobilized Human CD3E&CD3G Heterodimer Protein, His Tag&Tag Free (Cat. No. CDG-H52W5) at 1 μg/mL (100 μL/well) can bind Biotinylated Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3) (Cat. No. CDE-M525a) with a linear range of 2-16 ng/mL (QC tested).

  • Background
    CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Order Details

Price(USD) : $80.00

Price(USD) : $500.00

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