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ALK-7

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Cat. No. Species Product Description Structure Purity Feature
AL7-H52H5 Human Human ALK-7 Protein, His Tag
AL7-H52H5-structure
AL7-H52H5-sds
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Synonym Name

ALK-7,ACTR-IC,ACVR1C

Background

ALK-7 (Activin receptor-like kinase 7) is also known as Activin receptor type-1C, ACTR-IC, ACVR1C. Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.

Clinical and Translational Updates

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