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Your Position: Home > Integrin alpha 1 beta 1

Integrin alpha 1 beta 1

Brief Information

Name:Integrin alpha1/beta1
Target Synonym:Integrin alpha1beta1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Pending

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ACRO Quality

Part of Bioactivity data

IT1-R52W7-ELISA
 Integrin alpha 1 beta 1 ELISA

Immobilized Human Collagen I protein at 2 μg/mL (100 μL/well) can bind Rat ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-R52W7) with a linear range of 0.02-0.313 μg/mL (QC tested).

IN1-H52W9-MALS-HPLC
Integrin alpha 1 beta 1 MALS images

The purity of Human/Mouse ITGA1&ITGB1 Protein, His Tag&Tag Free (Cat. No. IN1-H52W9) is more than 85% and the molecular weight of this protein is around 260-300 kDa verified by SEC-MALS.

Synonym Name

Integrin alpha 1 beta 1,ITGA1&ITGB1

Background

Integrin alpha-1/beta-1 is a receptor for laminin and collagen. The Integrin alpha-1/beta-1 and Integrin alpha-2/beta-1 integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.

Clinical and Translational Updates

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