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Galectin-4

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Cat. No. Species Product Description Structure Purity Feature
GA4-M5247 Mouse Mouse Galectin-4 / LGALS4 / L36LBP Protein, His tag
GA4-M5247-structure
GA4-M5247-sds
GA4-H5246 Human Human Galectin-4 / LGALS4 / L36LBP Protein, His tag
GA4-H5246-structure
GA4-H5246-sds
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Synonym Name

LGALS4,L36LBP,Gal-4,Antigen NY-CO-27,Lactose-binding lectin 4

Background

Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.

Clinical and Translational Updates

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