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ANGPTL7

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Part of Bioactivity data

AN7-H52H5-SPR
 ANGPTL7 SPR

Human ANGPTL7, His Tag (Cat. No. AN7-H52H5) immobilized on CM5 Chip can bind Human LILRB4, His Tag (Cat. No. LI4-H52H7) with an affinity constant of 4.67 μM as determined in a SPR assay (Biacore T200) (Routinely tested).

AN7-H82F3-ELISA
 ANGPTL7 ELISA

Immobilized Human LILRB2, Fc Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Human ANGPTL7, Mouse IgG2a Fc,Avitag (Cat. No. AN7-H82F3) with a linear range of 0.156-2.5 μg/mL (QC tested).

Synonym Name

ANGPTL7,CDT6

Background

Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.

Clinical and Translational Updates

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