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DPPII

Brief Information

Name:Dipeptidyl peptidase II
Target Synonym:Dipeptidyl Arylamidase II,Carboxytripeptidase,Dipeptidyl Peptidase 2,DPP7,Dipeptidyl Peptidase 7,Dipeptidyl Peptidase II,Quiescent Cell Proline Dipeptidase,Dipeptidyl-Peptidase II,EC 3.4.14.2,DPP2,EC:3.4.14.2,DPPII,Dipeptidylpeptidase 7,Dipeptidyl Aminope
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Synonym Name

DPPII,QPP,DPP7,DPP2,Dipeptidyl peptidase 2,Dipeptidyl aminopeptidase II

Background

Dipeptidyl peptidase 2 (DPP2 or DPP II) is also known as Dipeptidyl peptidase 7 (DPP7), Quiescent cell proline dipeptidase (QPP), which belongs to the peptidase S28 family. DPP7 / DPP2 is detected in seminal plasma (at protein level). When the pH is 5.5, Dipeptidyl peptidase 2 display a optimum catalytic activity. DPP7 has low activity at pH 7 and is inactive at pH 8. DPP7 plays an important role in the degradation of some oligopeptides.

Clinical and Translational Updates

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