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Your Position: Home > GLP1R

GLP1R

Brief Information

Name:Glucagon-like peptide-1
Target Synonym:GLP-1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

Licensing

Project Name Modality Therapeutic Area Indications Stage Right Available
GLP-1/GIP/GCG fusion protein Fusion/Recombination protein Metabolic disease T2DM,Obesity IND Global
GLP-1/GIP/FGF21 fusion protein Fusion/Recombination protein Metabolic disease NASH,Type 2 diabetes,hyperlipidemia Preclinical Global  (except China)

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Part of Bioactivity data

CHEK-ATP160-Cell-based assay
 GLP1R FACS

Expression analysis of human GLP-1R on HEK293/Human GLP-1R Stable Cell Line by FACS.
Cell surface staining using PE-labeled anti-human GLP-1R antibody was performed on HEK293/Human GLP-1R Stable Cell Line with different expression levels: HEK293/Human GLP-1R Stable Cell Line (Low Expression); HEK293/Human GLP-1R Stable Cell Line (Medium Expression); HEK293/Human GLP-1R Stable Cell Line (High Expression).

CHEK-ATP161-Cell-based assay
 GLP1R FACS

Expression analysis of human GLP-1R on HEK293/Human GLP-1R Stable Cell Line by FACS.
Cell surface staining using PE-labeled anti-human GLP-1R antibody was performed on HEK293/Human GLP-1R Stable Cell Line with different expression levels: HEK293/Human GLP-1R Stable Cell Line (Low Expression); HEK293/Human GLP-1R Stable Cell Line (Medium Expression); HEK293/Human GLP-1R Stable Cell Line (High Expression).

GLR-H82E3-BLI
 GLP1R BLI

Loaded Biotinylated Human GLP1R, His,Avitag (Cat. No. GLR-H82E3) on NTA Biosensor, can bind GLP-1 (7-37) with an affinity constant of 1.40 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

GLR-H82E3-ELISA
 GLP1R ELISA

Immobilized Biotinylated Human GLP1R Protein, His,Avitag (Cat. No. GLR-H82E3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-GLP-R1 Antibody with a linear range of 0.5-31 ng/mL (QC tested).

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
HM-15275 HM-15275; HM15275 Phase 1 Clinical Hanmi Pharmaceutical Co Ltd Obesity Details

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