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SMN1

Brief Information

Name:Survival motor neuron protein
Target Synonym:Survival Of Motor Neuron 1 Isoform D345,Survival Of Motor Neuron 1 Isoform D2A2B3457,Survival Of Motor Neuron 1 Isoform D347,SMN1 more,SMN1,Survival Of Motor Neuron 1 Isoform D3457,Survival Of Motor Neuron 1, Telomeric,Gemin-1,Tudor Domain Containing 16A,SMNT,SMN,Survival Motor Neuron 1 Protein,Survival Motor Neuron Protein,T-BCD541,TDRD16A,BCD541,GEMIN1,SMA1,SMA2,SMA3,SMA4,SMA@,SMA,SMN Complex Proteins,Component of gems 1,SMN2,SMNC,Survival Of Motor Neuron 1 Isoform D2B3457,Survival Of Motor Ne
Number of Launched Drugs:3
Number of Drugs in Clinical Trials:5
Lastest Research Phase:Approved

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By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
SM1-H5145 Human Human SMN1 Protein, His Tag
SM1-H5145-structure
SM1-H5145-sds
ACRO Quality

Part of Bioactivity data

SM1-H5145-MALS-HPLC
 SMN1 ELISA

Immobilized Human SMN1, His Tag (Cat. No. SM1-H5145) at 1 μg/mL (100 μL/well) can bind Anti-SMN1 antibody with a linear range of 0.2-8 ng/mL (QC tested).

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Nusinersen sodium BIIB-058; ISIS-396443 Approved Ionis Pharmaceuticals Inc, Biogen Inc Spinraza United States Muscular Atrophy, Spinal Biogen Idec 2016-12-23 Muscular Atrophy, Spinal Details
Onasemnogene abeparvovec rAAV-9; AVXS-101; scAAV-9.CB.SMN; OAV101 Approved Novartis Gene Therapies Inc, Novartis Pharma Ag Zolgensma United States Muscular Atrophy, Spinal Novartis Gene Therapies Inc 2019-05-24 Spinal Muscular Atrophies of Childhood; Muscular Atrophy, Spinal Details
Risdiplam RG-7916; RO-7034067 Approved Ptc Therapeutics Inc EVRYSDI, 艾满欣 United States Muscular Atrophy, Spinal Genentech Inc 2020-08-07 Muscular Atrophy, Spinal Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
EXG001-307 EXG001-307 Phase 2 Clinical Hangzhou Jiayin Biotechnology Co Ltd Muscular Atrophy, Spinal Details
SMN-C3 SMN-C3 Phase 1 Clinical Ptc Therapeutics Inc, F. Hoffmann-La Roche Ltd Muscular Atrophy, Spinal Details
BIIB-115 BIIB-115; ION-306 Phase 1 Clinical Ionis Pharmaceuticals Inc Muscular Atrophy, Spinal Details
SKG-0201 SKG0201; SKG-0201 Phase 1 Clinical Skyline Therapeutics (Hong Kong) Ltd Spinal Muscular Atrophies of Childhood; Muscular Atrophy, Spinal Details
Branaplam LMI-070; NVS-SM1 Phase 2 Clinical Novartis Pharma Ag Huntington Disease; Muscular Atrophy, Spinal Details

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