Acrobiosystems for English
icon_bulk_orderBulk inquiry/Quick order
0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > FGF19

FGF19

Brief Information

Name:Fibroblast growth factor 19
Target Synonym:FGF-19
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

Product ListCompare or Buy

By Product Status:
By Product Category:
By Species:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
FG9-H51H3 Human Human FGF19 Protein, His Tag
FG9-H51H3-structure
FG9-H51H3-sds
FG9-H5253 Human Human FGF19 Protein, Fc Tag
FG9-H5253-structure
FG9-H5253-sds
ACRO Quality

Part of Bioactivity data

FG9-H51H3-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human FGF R4, Fc Tag (Cat. No. FG4-H5253) on Protein A Biosensor, can bind Human FGF19, His Tag (Cat. No. FG9-H51H3) with an affinity constant of 63.5 nM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

FG9-H51H3-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human FGF19, His Tag (Cat. No. FG9-H51H3) on HIS1K Biosensor, can bind Human FGF R4, Fc Tag (Cat. No. FG4-H5253) with an affinity constant of 16.6 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Customer Reviews

Synonym Name

FGF19/FGF-19/Fibroblast growth factor 19

Background

Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF–FGFR  was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.

Clinical and Translational Updates

This web search service is supported by Google Inc.

totop
Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
Fax
Fax
+1 888-377-6111
Address
Address
1 Innovation Way, Newark, DE 19711, USA

Leave a message